Donald J Chisholm
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Explore the profile of Donald J Chisholm including associated specialties, affiliations and a list of published articles.
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41
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1437
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Recent Articles
11.
Samaras K, Botelho N, Chisholm D, Lord R
Obesity (Silver Spring)
. 2009 Dec;
18(5):884-9.
PMID: 20019678
Type 2 diabetes mellitus (T2D) is predicted by central obesity and circulating adipokines regulating inflammation. We hypothesized that visceral adipose tissue (VAT) in T2D expresses greater levels of proinflammatory molecules....
12.
Milner K, van der Poorten D, Trenell M, Jenkins A, Xu A, Smythe G, et al.
Gastroenterology
. 2009 Dec;
138(3):932-41.e1-3.
PMID: 19962985
Background & Aims: Chronic hepatitis C (CHC) is associated with insulin resistance (IR), liver steatosis (genotype 3), and increased diabetes risk. The site and mechanisms of IR are unclear. Methods:...
13.
Samaras K, Botelho N, Chisholm D, Lord R
Obes Surg
. 2009 Sep;
20(1):108-13.
PMID: 19763711
Background: FTO gene variants are linked to obesity. We tested for site-specific differences in FTO gene expression in subcutaneous and visceral adipose tissue (SAT and VAT, respectively) from individuals with...
14.
Milner K, van der Poorten D, Xu A, Bugianesi E, Kench J, Lam K, et al.
Hepatology
. 2009 May;
49(6):1926-34.
PMID: 19475694
Unlabelled: Several circulating cytokines are increased with obesity and may combine with the influence of visceral fat to generate insulin resistance, inflammation, and fibrosis in nonalcoholic fatty liver disease (NAFLD)....
15.
Harmer A, Chisholm D, McKenna M, Hunter S, Ruell P, Naylor J, et al.
Diabetes Care
. 2008 Aug;
31(11):2097-102.
PMID: 18716051
Objective: To investigate sprint-training effects on muscle metabolism during exercise in subjects with (type 1 diabetic group) and without (control group) type 1 diabetes. Research Design And Methods: Eight subjects...
16.
van der Poorten D, Milner K, Hui J, Hodge A, Trenell M, Kench J, et al.
Hepatology
. 2008 Jul;
48(2):449-57.
PMID: 18627003
Unlabelled: Visceral obesity is intimately associated with metabolic disease and adverse health outcomes. However, a direct association between increasing amounts of visceral fat and end-organ inflammation and scarring has not...
17.
Li H, Heilbronn L, Hu D, Poynten A, Blackburn M, Shirkhedkar D, et al.
Obesity (Silver Spring)
. 2008 Feb;
16(2):356-62.
PMID: 18239644
Objective: To examine differences in gene expression between visceral (VF) and subcutaneous fat (SF) to identity genes of potential importance in regulation of VF. Methods And Procedures: We compared gene...
18.
Burt M, Johannsson G, Umpleby A, Chisholm D, Ho K
J Clin Endocrinol Metab
. 2008 Jan;
93(3):688-95.
PMID: 18182447
Context: Chronic pharmacological glucocorticoid (GC) use causes substantial morbidity from protein wasting. GH and androgens are anabolic agents that may potentially reverse GC-induced protein loss. Objective: Our objective was to...
19.
Gail Trapp E, Chisholm D, Boutcher S
Am J Physiol Regul Integr Comp Physiol
. 2007 Sep;
293(6):R2370-5.
PMID: 17898114
The metabolic response to two different forms of high-intensity intermittent cycle exercise was investigated in young women. Subjects (8 trained and 8 untrained) performed two bouts of high-intensity intermittent exercise:...
20.
Burt M, Johannsson G, Umpleby A, Chisholm D, Ho K
J Clin Endocrinol Metab
. 2007 Jul;
92(10):3923-9.
PMID: 17652216
Context: High-dose glucocorticoids cause acute protein loss by increasing protein breakdown and oxidation. Whether lower glucocorticoid doses, typical of therapeutic use, induce sustained catabolism has not been studied. Objective: Our...