Donald F Newgreen
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Explore the profile of Donald F Newgreen including associated specialties, affiliations and a list of published articles.
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69
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2949
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Recent Articles
1.
Yang W, Pham J, King S, Newgreen D, Young H, Stamp L, et al.
Biomolecules
. 2022 Aug;
12(8).
PMID: 36008996
Hirschsprung disease (HSCR) is characterised by the absence of enteric ganglia along variable lengths of the distal bowel. Current gold standard treatment involves the surgical resection of the defective, aganglionic...
2.
Abu-Bonsrah K, Newgreen D, Dottori M
Cells
. 2021 Nov;
10(11).
PMID: 34831120
Medullary thyroid carcinoma contributes to about 3-4% of thyroid cancers and affects C cells rather than follicular cells. Thyroid C cell differentiation from human pluripotent stem cells has not been...
3.
MacKenzie K, Garritsen R, Chauhan R, Sribudiani Y, de Graaf B, Rugenbrink T, et al.
Int J Mol Sci
. 2021 Nov;
22(22).
PMID: 34830235
Patients with Hirschsprung disease (HSCR) do not always receive a genetic diagnosis after routine screening in clinical practice. One of the reasons for this could be that the causal mutation...
4.
Yang J, Antin P, Berx G, Blanpain C, Brabletz T, Bronner M, et al.
Nat Rev Mol Cell Biol
. 2021 Oct;
22(12):834.
PMID: 34654908
No abstract available.
5.
Nagy N, Guyer R, Hotta R, Zhang D, Newgreen D, Halasy V, et al.
Development
. 2020 Sep;
147(21).
PMID: 32994173
Appropriately balanced RET signaling is of crucial importance during embryonic neural crest cell migration, proliferation and differentiation. RET deficiency, for example, leads to intestinal aganglionosis (Hirschsprung disease), whereas overactive RET...
6.
Yang J, Antin P, Berx G, Blanpain C, Brabletz T, Bronner M, et al.
Nat Rev Mol Cell Biol
. 2020 Apr;
21(6):341-352.
PMID: 32300252
Epithelial-mesenchymal transition (EMT) encompasses dynamic changes in cellular organization from epithelial to mesenchymal phenotypes, which leads to functional changes in cell migration and invasion. EMT occurs in a diverse range...
7.
Hao M, Bergner A, Newgreen D, Enomoto H, Young H
Methods Mol Biol
. 2019 Apr;
1976:97-105.
PMID: 30977068
Time-lapse imaging of gut explants from embryonic mice in which neural crest-derived cells express fluorescent proteins allows the behavior of enteric neural crest cells to be observed and analyzed. Explants...
8.
Abu-Bonsrah K, Viventi S, Newgreen D, Dottori M
Methods Mol Biol
. 2019 Apr;
1976:37-47.
PMID: 30977063
There are a vast range of diseases and disorders that are neurocristopathic in origin, including Hirschsprung's disease, pheochromocytoma, familial dysautonomia, craniofacial disorders, and melanomas. Having a source of human neural...
9.
Newgreen D, Landman K, Osborne J
Methods Mol Biol
. 2019 Apr;
1976:21-36.
PMID: 30977062
Mathematical modeling can allow insight into the biological processes that can be difficult to access by conventional biological means alone. Such projects are becoming increasingly attractive with the appearance of...
10.
Zhang D, Rollo B, Nagy N, Stamp L, Newgreen D
Dev Biol
. 2018 Dec;
446(1):34-42.
PMID: 30529057
Cells of the vagal neural crest (NC) form most of the enteric nervous system (ENS) by a colonising wave in the embryonic gut, with high cell proliferation and differentiation. Enteric...