Dominga Lapi
Overview
Explore the profile of Dominga Lapi including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
40
Citations
294
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Chiarugi S, Margheriti F, De Lorenzi V, Martino E, Margheritis E, Moscardini A, et al.
Cell Chem Biol
. 2025 Feb;
PMID: 39999832
Thiazide and thiazide-like diuretics are among the most efficacious and used drugs for the treatment of hypertension, edema, and major cardiovascular outcomes. Despite more then than six decades of clinical...
2.
Lapi D, Tenore G, Federighi G, Chiurazzi M, Nunziato S, Lonardo M, et al.
Int J Mol Sci
. 2024 Oct;
25(19).
PMID: 39409196
Acute and chronic hypertension causes cerebral vasculopathy, increasing the risk of ischemia and stroke. Our study aimed to compare the effects of arterial pressure reduction on the pial microvascular responses...
3.
Milano S, Saponara I, Gerbino A, Lapi D, Lela L, Carmosino M, et al.
Front Physiol
. 2024 Mar;
15:1304375.
PMID: 38455846
Efferent sympathetic nerve fibers regulate several renal functions activating norepinephrine receptors on tubular epithelial cells. Of the beta-adrenoceptors (β-ARs), we previously demonstrated the renal expression of β3-AR in the thick...
4.
Sabatino L, Lapi D, Del Seppia C
Biomolecules
. 2024 Feb;
14(2).
PMID: 38397435
Thyroid hormones (THs) are essential in normal brain development, and cognitive and emotional functions. THs act through a cascade of events including uptake by the target cells by specific cell...
5.
Lucchesi M, Marracci S, Amato R, Lapi D, Santana-Garrido A, Espinosa-Martin P, et al.
Nutrients
. 2024 Feb;
16(3).
PMID: 38337691
Glaucoma is characterized by cupping of the optic disc, apoptotic degeneration of retinal ganglion cells (RGCs) and their axons, and thinning of the retinal nerve fiber layer, with patchy loss...
6.
Guidotti L, Tomassi E, Marracci S, Lai M, Lapi D, Pesi R, et al.
Int J Mol Sci
. 2023 Dec;
24(24).
PMID: 38139245
Cisplatin is a chemotherapeutic drug for the treatment of several solid tumors, whose use is limited by its nephrotoxicity, neurotoxicity, ototoxicity, and development of resistance. The toxicity is caused by...
7.
Lapi D, Federighi G, Lonardo M, Chiurazzi M, Muscariello E, Tenore G, et al.
Front Physiol
. 2023 Feb;
14:1091889.
PMID: 36755790
Oxidative stress is implicated in the pathogenesis of arterial hypertension. The reduction in the bioavailability of nitric oxide (NO) causes endothelial dysfunction, altering the functions of cerebral blood vessels. Physical...
8.
Melecchi A, Amato R, Lapi D, Dal Monte M, Rusciano D, Bagnoli P, et al.
Front Pharmacol
. 2022 Oct;
13:1038730.
PMID: 36313376
Age-related macular degeneration (AMD) is nowadays considered among the retinal diseases whose clinical management lacks established treatment approaches, mainly for its atrophic (dry) form. In this respect, the use of...
9.
Lapi D, Cammalleri M, Dal Monte M, Di Maro M, Santillo M, Belfiore A, et al.
Biomolecules
. 2021 Dec;
11(12).
PMID: 34944506
Renin-angiotensin systems produce angiotensin II (Ang II) and angiotensin 1-7 (Ang 1-7), which are able to induce opposite effects on circulation. This study in vivo assessed the effects induced by...
10.
Milano S, Carmosino M, Gerbino A, Saponara I, Lapi D, Dal Monte M, et al.
Front Physiol
. 2021 Sep;
12:695824.
PMID: 34483955
We previously showed that the beta-3 adrenergic receptor (BAR3) is expressed in most segments of the nephron where its agonism promotes a potent antidiuretic effect. We localized BAR3 in distal...