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Lina Sabatino

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Articles 51
Citations 851
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Recent Articles
1.
Pranzini E, Muccillo L, Nesi I, Santi A, Mancini C, Lori G, et al.
Cell Death Discov . 2024 Dec; 10(1):510. PMID: 39706853
Cancer cachexia is a multifactorial syndrome characterized by a progressive loss of body weight occurring in about 80% of cancer patients, frequently representing the leading cause of death. Dietary intervention...
2.
Spaziani S, Esposito A, Barisciano G, Quero G, Elumalai S, Leo M, et al.
J Nanobiotechnology . 2024 Jun; 22(1):350. PMID: 38902746
Background: Breast cancer (BC) is a heterogeneous neoplasm characterized by several subtypes. One of the most aggressive with high metastasis rates presents overexpression of the human epidermal growth factor receptor...
3.
Caputo T, Barisciano G, Mule C, Cusano A, Aliberti A, Muccillo L, et al.
Int J Nanomedicine . 2023 Nov; 18:6999-7020. PMID: 38034948
Background: Trastuzumab, a therapeutic monoclonal antibody directed against HER2, is routinely used to treat HER2-positive breast cancer with a good response rate. However, concerns have arisen in the clinical practice...
4.
Fosso E, Leo M, Muccillo L, Mandrone V, Di Meo M, Molinario A, et al.
Antioxidants (Basel) . 2023 Aug; 12(8). PMID: 37627542
Quercetin (Qc) inhibits cell proliferation and induces apoptosis in a variety of cancer cells. The molecular mechanism of action has not been fully elucidated; however, interplay with some miRNAs has...
5.
Leo M, Muccillo L, Pranzini E, Barisciano G, Parri M, Lopatriello G, et al.
Cells . 2022 Dec; 11(24). PMID: 36552757
Oil production waste products (OPWPs) derive from olive mill and represent a crucial environmental problem due to their high polyphenolic content able to pollute the ground. One option to reduce...
6.
Leo M, Sabatino L
Int J Mol Sci . 2022 Oct; 23(20). PMID: 36293358
Biological therapy, with its multifaceted applications, has revolutionized the treatment of tumors, mainly due to its ability to exclusively target cancer cells and reduce the adverse effects on normal tissues....
7.
Pranzini E, Pardella E, Muccillo L, Leo A, Nesi I, Santi A, et al.
Cell Rep . 2022 Aug; 40(7):111233. PMID: 35977477
5-Fluorouracil (5-FU) is a key component of chemotherapy for colorectal cancer (CRC). 5-FU efficacy is established by intracellular levels of folate cofactors and DNA damage repair strategies. However, drug resistance...
8.
Mezzapelle R, Leo M, Caprioglio F, Colley L, Lamarca A, Sabatino L, et al.
Cancers (Basel) . 2022 May; 14(9). PMID: 35565443
CXCR4 is a G-Protein coupled receptor that is expressed nearly ubiquitously and is known to control cell migration via its interaction with CXCL12, the most ancient chemokine. The functions of...
9.
Leo M, Muccillo L, Dugo L, Bernini R, Santi L, Sabatino L
Antioxidants (Basel) . 2022 Apr; 11(4). PMID: 35453308
Olive oil production is associated with the generation of oil production waste products (OPWPs) rich in water-soluble polyphenols that represent serious environmental problems. Yet OPWPs can offer new opportunities by...
10.
Colangelo T, Carbone A, Mazzarelli F, Cuttano R, Dama E, Nittoli T, et al.
Cell Death Differ . 2022 Jan; 29(8):1552-1568. PMID: 35034102
The circadian gene Timeless (TIM) provides a molecular bridge between circadian and cell cycle/DNA replication regulatory systems and has been recently involved in human cancer development and progression. However, its...