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Do Young Hyeon

Explore the profile of Do Young Hyeon including associated specialties, affiliations and a list of published articles. Areas
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Articles 26
Citations 666
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Recent Articles
1.
Hyeon D, Nam D, Shin H, Jeong J, Jung E, Cho S, et al.
Mol Cancer . 2025 Mar; 24(1):77. PMID: 40087745
We report proteogenomic analysis of locally advanced cervical cancer (LACC). Exome-seq data revealed predominant alterations of keratinization-TP53 regulation and O-glycosylation-TP53 regulation axes in squamous and adeno-LACC, respectively, compared to in...
2.
Han S, Kim B, Hyeon D, Jeong D, Ryu J, Nam J, et al.
Nat Commun . 2024 Oct; 15(1):8628. PMID: 39366998
The IL-23-Th17 axis is responsible for neutrophilic inflammation in various inflammatory diseases. Here, we discover a potential pathway to inhibit neutrophilic asthma. In our neutrophil-dominant asthma (NDA) model, single-cell RNA-seq...
3.
Kim M, Hyeon D, Kim K, Hwang D, Lee Y
Plant Physiol . 2024 Mar; 195(4):2694-2711. PMID: 38527800
Airspace or aerenchyma is crucial for plant development and acclimation to stresses such as hypoxia, drought, and nutritional deficiency. Although ethylene-mediated signaling cascades are known to regulate aerenchyma formation in...
4.
Chung H, Lee G, Nam S, Lee J, Han J, Song S, et al.
Brain . 2024 Jan; 147(6):2114-2127. PMID: 38227798
Mutations in the Microrchidia CW-type zinc finger 2 (MORC2) GHKL ATPase module cause a broad range of neuropathies, such as Charcot-Marie-Tooth disease type 2Z; however, the aetiology and therapeutic strategy...
5.
Hyeon D, Nam D, Han Y, Kim D, Kim G, Kim D, et al.
Nat Cancer . 2023 May; 4(5):774. PMID: 37208505
No abstract available.
6.
Hyeon D, Nam D, Han Y, Kim D, Kim G, Kim D, et al.
Nat Cancer . 2022 Dec; 4(2):290-307. PMID: 36550235
We report a proteogenomic analysis of pancreatic ductal adenocarcinoma (PDAC). Mutation-phosphorylation correlations identified signaling pathways associated with somatic mutations in significantly mutated genes. Messenger RNA-protein abundance correlations revealed potential prognostic...
7.
Kim D, Jeong J, Lee D, Hyeon D, Park G, Jeon S, et al.
Nat Commun . 2022 Oct; 13(1):6292. PMID: 36272973
Pancreatic ductal adenocarcinoma (PDAC) has a poor 5-year overall survival rate. Patients with PDAC display limited benefits after undergoing chemotherapy or immunotherapy modalities. Herein, we reveal that chemotherapy upregulates placental...
8.
Jeong J, Jung I, Kim J, Jeon S, Hyeon D, Min H, et al.
Cell Death Differ . 2022 Apr; 29(11):2151-2162. PMID: 35473985
Hematopoiesis occurs within a unique bone marrow (BM) microenvironment, which consists of various niche cells, cytokines, growth factors, and extracellular matrix components. These multiple components directly or indirectly regulate the...
9.
Choi B, Hyeon D, Lee J, Long T, Hwang D, Hwang I
Mol Cells . 2022 Apr; 45(5):294-305. PMID: 35422451
E3 ligase BRUTUS (BTS), a putative iron sensor, is expressed in both root and shoot tissues in seedlings of . The role of in root tissues has been well established....
10.
Park S, Park S, Kim Y, Hyeon D, Park H, Jeong J, et al.
Plant Cell Environ . 2022 Mar; 45(6):1719-1733. PMID: 35312081
Leaf senescence proceeds with age but is modulated by various environmental stresses and hormones. Salt stress is one of the most well-known environmental stresses that accelerate leaf senescence. However, the...