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Dmitriy V Bagaev

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Recent Articles
1.
Shugay M, Bagaev D, Zvyagin I, Vroomans R, Crawford J, Dolton G, et al.
Nucleic Acids Res . 2017 Oct; 46(D1):D419-D427. PMID: 28977646
The ability to decode antigen specificities encapsulated in the sequences of rearranged T-cell receptor (TCR) genes is critical for our understanding of the adaptive immune system and promises significant advances...
2.
Shugay M, Zaretsky A, Shagin D, Shagina I, Volchenkov I, Shelenkov A, et al.
PLoS Comput Biol . 2017 May; 13(5):e1005480. PMID: 28475621
Unique molecular identifiers (UMIs) show outstanding performance in targeted high-throughput resequencing, being the most promising approach for the accurate identification of rare variants in complex DNA samples. This approach has...
3.
Bagaev D, Zvyagin I, Putintseva E, Izraelson M, Britanova O, Chudakov D, et al.
BMC Genomics . 2016 Jun; 17:453. PMID: 27297497
Background: The repertoire of T- and B-cell receptor sequences encodes the antigen specificity of adaptive immunity system, determines its present state and guides its ability to mount effective response against...
4.
Shugay M, Bagaev D, Turchaninova M, Bolotin D, Britanova O, Putintseva E, et al.
PLoS Comput Biol . 2015 Nov; 11(11):e1004503. PMID: 26606115
Despite the growing number of immune repertoire sequencing studies, the field still lacks software for analysis and comprehension of this high-dimensional data. Here we report VDJtools, a complementary software suite...