Dirk Hoffmann
Overview
Explore the profile of Dirk Hoffmann including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
40
Citations
592
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
11.
Lange L, Hoffmann D, Schwarzer A, Ha T, Philipp F, Lenz D, et al.
Stem Cell Reports
. 2019 Dec;
14(1):122-137.
PMID: 31839543
Induced pluripotent stem cells (iPSCs) offer a promising platform to model early embryonic developmental processes, to create disease models that can be evaluated by drug screens as well as proof-of-concept...
12.
Klatt D, Cheng E, Hoffmann D, Santilli G, Thrasher A, Brendel C, et al.
Hum Gene Ther
. 2019 Nov;
31(3-4):199-210.
PMID: 31773990
Targeted integration into a genomic safe harbor, such as the locus on chromosome 19, promises predictable transgene expression and reduces the risk of insertional mutagenesis in the host genome. The...
13.
Klatt D, Cheng E, Philipp F, Selich A, Dahlke J, Schmidt R, et al.
Stem Cell Reports
. 2019 Sep;
13(4):590-598.
PMID: 31543470
Mutations in the NADPH oxidase, which is crucial for the respiratory burst in phagocytes, result in chronic granulomatous disease (CGD). The only curative treatment option for CGD patients, who suffer...
14.
Philipp F, Selich A, Rothe M, Hoffmann D, Rittinghausen S, Morgan M, et al.
Stem Cell Reports
. 2018 Oct;
11(5):1051-1060.
PMID: 30344010
Hematopoietic stem cells (HSCs) ensure a life-long regeneration of the blood system and are therefore an important source for transplantation and gene therapy. The teratoma environment supports the complex development...
15.
van Diepen L, Buettner F, Hoffmann D, Thiesler C, von Bohlen Und Halbach O, von Bohlen Und Halbach V, et al.
Eur J Hum Genet
. 2018 Aug;
26(12):1773-1783.
PMID: 30089820
ST3GAL3 encodes the Golgi enzyme beta-galactoside-alpha-2,3-sialyltransferase-III that in humans forms, among others, the sialyl Lewis a (sLe) epitope on proteins. Functionally deleterious variants in this gene were previously identified in...
16.
Geis F, Galla M, Hoffmann D, Kuehle J, Zychlinski D, Maetzig T, et al.
Retrovirology
. 2017 Oct;
14(1):48.
PMID: 29047401
The authors wish to apologize for an error within the scale bar of the microarray heatmap in Additional File 5 of the supplementary information. Two values were incorrectly displayed on...
17.
Kunkiel J, Godecke N, Ackermann M, Hoffmann D, Schambach A, Lachmann N, et al.
Sci Rep
. 2017 Aug;
7(1):7919.
PMID: 28801671
Suppression of therapeutic transgene expression from retroviral gene therapy vectors by epigenetic defence mechanisms represents a problem that is particularly encountered in pluripotent stem cells (PSCs) and their differentiated progeny....
18.
Geis F, Galla M, Hoffmann D, Kuehle J, Zychlinski D, Maetzig T, et al.
Retrovirology
. 2017 Jun;
14(1):34.
PMID: 28569216
Background: Retroviral vectors are derived from wild-type retroviruses, can be used to study retrovirus-host interactions and are effective tools in gene and cell therapy. However, numerous cell types are resistant...
19.
Rimkus G, Hoffmann D
Food Addit Contam Part A Chem Anal Control Expo Risk Assess
. 2017 Apr;
34(6):950-961.
PMID: 28406359
Chloramphenicol (CAP) is a broad-spectrum antibiotic used widely in both human and veterinary medication. Since 1994, CAP has not been authorised for use in food-producing animals in the European Union...
20.
Hubner J, Hoseini S, Suerth J, Hoffmann D, Maluski M, Herbst J, et al.
Mol Ther
. 2016 May;
24(7):1216-26.
PMID: 27138041
Retroviral engineering of hematopoietic stem cell-derived precursor T-cells (preTs) opens the possibility of targeted T-cell transfer across human leukocyte antigen (HLA)-barriers. Alpharetroviral vectors exhibit a more neutral integration pattern thereby...