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Dipta Sengupta

Explore the profile of Dipta Sengupta including associated specialties, affiliations and a list of published articles. Areas
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Articles 25
Citations 631
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Recent Articles
1.
Holzenspies J, Sengupta D, Bickmore W, Brickman J, Illingworth R
PLoS Genet . 2025 Jan; 21(1):e1011584. PMID: 39883738
The genetic circuitry that encodes the developmental programme of mammals is regulated by transcription factors and chromatin modifiers. During early gestation, the three embryonic germ layers are established in a...
2.
Sengupta D, Deb M, Kar S, Pradhan N, Parbin S, Kirtana R, et al.
Semin Cancer Biol . 2020 Jun; 72:46-64. PMID: 32497683
MicroRNAs (miRNAs) are key epigenomic regulators of biological processes in animals and plants. These small non coding RNAs form a complex networks that regulate cellular function and development. MiRNAs prevent...
3.
Boyle S, Flyamer I, Williamson I, Sengupta D, Bickmore W, Illingworth R
Genes Dev . 2020 May; 34(13-14):931-949. PMID: 32439634
Polycomb group (PcG) proteins silence gene expression by chemically and physically modifying chromatin. A subset of PcG target loci are compacted and cluster in the nucleus; a conformation that is...
4.
Kumar Y, Sengupta D, Bickmore W
J Biosci . 2020 Jan; 45. PMID: 31965996
The mammalian genome is complex and presents a dynamic structural organization that reflects function. Organization of the genome inside the mammalian nucleus impacts all nuclear processes including but not limited...
5.
Benabdallah N, Williamson I, Illingworth R, Kane L, Boyle S, Sengupta D, et al.
Mol Cell . 2019 Sep; 76(3):473-484.e7. PMID: 31494034
Enhancers can regulate the promoters of their target genes over very large genomic distances. It is widely assumed that mechanisms of enhancer action involve the reorganization of three-dimensional chromatin architecture,...
6.
Pradhan N, Parbin S, Kausar C, Kar S, Mawatwal S, Das L, et al.
Food Chem Toxicol . 2019 May; 130:161-173. PMID: 31112703
Aberrant epigenetic modifications are responsible for tumor development and cancer progression; however, readily reversible. Bioactive molecules from diets are promising to cure cancer by modulating epigenetic marks and changing immune...
7.
Sengupta D, Deb M, Kar S, Parbin S, Pradhan N, Patra S
Gene . 2019 Apr; 705:22-35. PMID: 31005612
Mixed-lineage leukaemia 1 (MLL1) enzyme plays major role in regulating genes associated with vertebrate development. Cell physiology and homeostasis is regulated by microRNAs in diverse microenvironment. In this investigation we...
8.
Pradhan N, Parbin S, Kar S, Das L, Kirtana R, Suma Seshadri G, et al.
Biochim Biophys Acta Mol Basis Dis . 2019 Apr; 1865(6):1651-1665. PMID: 30954555
Loss of E-cadherin and epithelial to mesenchymal transition (EMT) are key steps in cancer progression. Reactive oxygen species (ROS) play significant roles in cellular physiology and homeostasis. Roles of E-cadherin...
9.
Parbin S, Pradhan N, Das L, Saha P, Deb M, Sengupta D, et al.
Exp Cell Res . 2018 Dec; 374(2):323-332. PMID: 30528566
Microtubule associated tumor suppressor 1 (MTUS1) has been recognized as a tumor suppressor gene in multiple cancers. However, the molecular mechanisms underlying the regulation of MTUS1 are yet to be...
10.
Sengupta D, Deb M, Patra S
Gene . 2018 Mar; 660:68-79. PMID: 29596883
Functional analyses of noncoding RNAs have associated many micro RNAs (miRNA, miR) with various physiological processes, including proliferation, differentiation, development, cell metabolism, and apoptosis. Aberrant expression of miRNA and imbalance...