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Dionisia Sepulveda

Explore the profile of Dionisia Sepulveda including associated specialties, affiliations and a list of published articles. Areas
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Articles 23
Citations 307
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Recent Articles
1.
Duran A, Venegas M, Barahona S, Sepulveda D, Baeza M, Cifuentes V, et al.
Biol Res . 2024 Nov; 57(1):78. PMID: 39497228
The yeast Xanthophyllomyces dendrorhous synthesizes astaxanthin, a high-value carotenoid with biotechnological relevance in the nutraceutical and aquaculture industries. However, enhancing carotenoid production through strain engineering remains an ongoing challenge. Recent...
2.
Venegas M, Duran A, Campusano S, Barahona S, Sepulveda D, Baeza M, et al.
Biomolecules . 2024 Jul; 14(7). PMID: 39062491
The sterol regulatory element-binding protein (SREBP) pathway is an integral cellular mechanism that regulates lipid homeostasis, in which transcriptional activator SREBPs regulate the expression of various genes. In the carotenogenic...
3.
Baeza M, Sepulveda D, Cifuentes V, Alcaino J
Front Microbiol . 2024 Jul; 15:1414422. PMID: 39040903
Codon usage bias (CUB) has been described in viruses, prokaryotes, and eukaryotes and has been linked to several cellular and environmental factors, such as the organism's growth temperature, gene expression...
4.
Sepulveda D, Campusano S, Moline M, Barahona S, Baeza M, Alcaino J, et al.
Int J Mol Sci . 2023 Mar; 24(6). PMID: 36983003
The UCD 67-385 genome harbors a 7873 bp cluster containing , and , encoding 2-desmethy-4-deoxygadusol synthase, O-methyl transferase, and ATP-grasp ligase, respectively, of the mycosporine glutaminol (MG) biosynthesis pathway. Homozygous...
5.
Martinez-Moya P, Campusano S, Sepulveda D, Paradela A, Alcaino J, Baeza M, et al.
Int J Mol Sci . 2022 Aug; 23(16). PMID: 36012547
is a natural source of astaxanthin and mycosporines. This yeast has been isolated from high and cold mountainous regions around the world, and the production of these secondary metabolites may...
6.
Gonzalez A, Venegas M, Barahona S, Gomez M, Gutierrez M, Sepulveda D, et al.
J Lipid Res . 2022 Feb; 63(3):100175. PMID: 35120994
Cytochrome P450s (P450s) are heme-containing proteins involved in several cellular functions, including biosynthesis of steroidal hormones, detoxification of xenobiotic compounds, among others. Damage response protein 1 (Dap1) has been described...
7.
Gomez M, Campusano S, Gutierrez M, Sepulveda D, Barahona S, Baeza M, et al.
J Lipid Res . 2020 Sep; 61(12):1658-1674. PMID: 32933952
is a basidiomycete yeast that produces carotenoids, mainly astaxanthin. Astaxanthin is an organic pigment of commercial interest due to its antioxidant and coloring properties. has a functional SREBP pathway, and...
8.
Venegas M, Barahona S, Gonzalez A, Sepulveda D, Zuniga G, Baeza M, et al.
Front Microbiol . 2020 Jul; 11:1312. PMID: 32612595
synthesizes astaxanthin, a carotenoid used in aquaculture. Astaxanthin is synthesized from metabolites of the mevalonate pathway, which are also precursors for sterols biosynthesis. The interruption of the gene, which is...
9.
Martinez-Moya P, Campusano S, Cordova P, Paradela A, Sepulveda D, Alcaino J, et al.
mSphere . 2020 Apr; 5(2). PMID: 32238568
is a carotenogenic yeast with a singular metabolic capacity to produce astaxanthin, a valuable antioxidant pigment. This yeast can assimilate several carbon sources and sustain fermentation even under aerobic conditions....
10.
Gomez M, Gutierrez M, Gonzalez A, Garate-Castro C, Sepulveda D, Barahona S, et al.
J Lipid Res . 2019 Dec; 61(2):229-243. PMID: 31806730
is a basidiomycete yeast known as a natural producer of astaxanthin, a carotenoid of commercial interest because of its antioxidant properties. Recent studies indicated that has a functional SREBP pathway...