Dina A Hanna

Overview

Explore the profile of Dina A Hanna including associated specialties, affiliations and a list of published articles.

Snapshot

Articles 4

Citations 12

Followers 0

Related Specialties

Pharmacology

Allergy & Immunology

Biochemistry

Co-Authors

Ali A Abo-Saif

Amany A Azouz

Basim Anwar Shehata Messiha

Marwa M Abdelhakeem

Phoebe F Lamie

Fares E M Ali

Martha M Morcoss

Marwa M Khalaf

Basim A S Messiha

Published In

Immunopharmacol Immunotoxicol

Bioorg Chem

Saudi Pharm J

Int Immunopharmacol

Affiliations

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Recent Articles

Design, synthesis and in silico insights of novel 1,2,3-triazole benzenesulfonamide derivatives as potential carbonic anhydrase IX and XII inhibitors with promising anticancer activity

Abdelhakeem M, Morcoss M, Hanna D, Lamie P

Bioorg Chem . 2024 Feb; 144:107154. PMID: 38309003

Novel 1,2,3-triazole benzenesulfonamide derivatives were designed as inhibitors for the tumor- related hCA IX and XII isoforms. Most of the synthesized compounds showed good inhibitory activity against hCA IX and...

Lysosomal membrane stabilization by imipramine attenuates gentamicin-induced renal injury: Enhanced LAMP2 expression, down-regulation of cytoplasmic cathepsin D and tBid/cytochrome c/cleaved caspase-3 apoptotic signaling

Hanna D, Messiha B, Abo-Saif A, Ali F, Azouz A

Int Immunopharmacol . 2023 Nov; 126:111179. PMID: 37995569

Nephrotoxicity is a serious complication commonly encountered with gentamicin (GTM) treatment. Permeabilization of lysosomes with subsequent cytoplasmic release of GTM and cathepsins is considered a crucial issue in progression of...

Interference with megalin expression/endocytic function by montelukast mitigates gentamicin nephrotoxicity: Downregulation of ClC-5 expression

Azouz A, Hanna D, Abo-Saif A, Messiha B

Saudi Pharm J . 2022 May; 30(2):150-161. PMID: 35528850

Megalin receptor-mediated endocytosis participates a crucial role in gentamicin (GM) uptake, accumulation, and toxicity. In this study, we investigated the potential effects of montelukast (MLK) on megalin expression/endocytic function against...

Polydatin protects against ovalbumin-induced bronchial asthma in rats; involvement of urocortin and surfactant-D expression

Hanna D, Khalaf M, Abo-Saif A

Immunopharmacol Immunotoxicol . 2018 Nov; 41(3):403-412. PMID: 30422021

Prevalence of bronchial asthma massively increases worldwide, while the frequent therapies are still not sufficient. Polydatin, a naturally occurring glycoside, was known as to have anti-inflammatory and anti-oxidant effects. The...