Marwa M Khalaf
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Explore the profile of Marwa M Khalaf including associated specialties, affiliations and a list of published articles.
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27
Citations
239
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Recent Articles
1.
Sharata E, Attya M, Khalaf M, Rofaeil R, Abo-Youssef A, Hemeida R
Int Immunopharmacol
. 2025 Mar;
152:114384.
PMID: 40056515
Aim: This study aims to investigate the potential protective effect of levomilnacipran (LVM) against cyclophosphamide (CPA)-induced hepatotoxicity by targeting α-Klotho/TLR4/p38-MAPK/NF-κB p65 and Caspase-3-dependent apoptosis signaling pathways. Main Methods: The toxicity...
2.
Abdelaala N, El-Shoura E, Khalaf M, Zafaar D, A N Ahmed A, Atwa A, et al.
Immunopharmacol Immunotoxicol
. 2025 Feb;
:1-18.
PMID: 40017009
Purpose: Amikacin (AMC), an aminoglycoside antibiotic known for its rapid and potent bactericidal activity, is also associated with nephrotoxicity. Diosmin and perindopril have been reported to improve renal function and...
3.
Khalaf M, Hassanein E, Qebesy H, Ahmed A, Mahmoud H
Tissue Cell
. 2025 Jan;
93:102744.
PMID: 39855027
Doxorubicin (DOX) is an anthracycline chemotherapy employed in treating malignancies. Unfortunately, the clinical application of DOX is limited due to its nephrotoxicity. Granisetron (GRAN) is a 5-HT3 receptor blocker used...
4.
Khalaf M, Malak M, Alsahli T, Althobaiti M, Hamzawy M, Abdel-Fattah M
Fundam Clin Pharmacol
. 2025 Jan;
39(1):e13052.
PMID: 39801131
Drug repurposing of well-established drugs to be targeted against lung cancer has been a promising strategy. Bosentan is an endothelin 1 (ET-1) blocker widely used in pulmonary hypertension. The current...
5.
El-Sawy W, Khalaf M, El-Bahrawy A, Messiha B, Hemeida R
Naunyn Schmiedebergs Arch Pharmacol
. 2024 Dec;
PMID: 39625489
Purpose: Among the most undesirable effects that lead to the restriction of doxorubicin (DOX) use in chemotherapy is kidney damage. This research aimed to assess the possible defenses against DOX-induced...
6.
Khalaf M, Mahmoud H, Kandeil M, Mahmoud H, Salama A
Drug Chem Toxicol
. 2024 Nov;
47(6):897-908.
PMID: 39563658
Depression is a persistent illness affecting health, behavior, and performance in life. Worldwide morbidity and mortality are caused by depression. The current study intended to explore fumaric acid's potential protective...
7.
Ezz-Eldin Y, El-Din Ewees M, Khalaf M, Azouz A
Eur J Pharmacol
. 2024 Oct;
984:177069.
PMID: 39442744
Metabolic dysfunction-associated steatohepatitis (MASH) is a chronic liver disorder marked by hepatic fat accumulation and inflammatory infiltrates which may evolve to cirrhosis. Clinical studies have demonstrated the higher risk of...
8.
El-Sawy W, El-Bahrawy A, Messiha B, Hemeida R, Khalaf M
Food Chem Toxicol
. 2024 Jul;
191:114863.
PMID: 38997059
Antioxidants given concurrently with chemotherapy offer an effective strategy for reducing the negative effects of the drug. One remaining obstacle to the use of doxorubicin (DOX) in chemotherapy is cardiotoxicity....
9.
Ezz-Eldin Y, Ewees M, Azouz A, Khalaf M
Naunyn Schmiedebergs Arch Pharmacol
. 2024 Jun;
397(11):9067-9079.
PMID: 38884676
Non-alcoholic steatohepatitis (NASH) is a severe liver condition characterized by excessive fat deposition, ballooning, and lobular inflammation. This investigation was conducted to estimate the capability of concomitant tamoxifen administration (TAM)...
10.
Elnaggar M, Hafez H, Abdallah A, Hamza M, Khalaf M, El-Haddad A
J Oncol Pharm Pract
. 2023 Aug;
30(6):983-991.
PMID: 37528663
Background/objectives: Cyclosporine A (CSA) dosing has been complicated by considerable intra-patient and inter-patient variability in pharmacokinetics, which is affected by different factors. We aimed to assess the various factors that...