Dimitrios Trafalis
Overview
Explore the profile of Dimitrios Trafalis including associated specialties, affiliations and a list of published articles.
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16
Citations
65
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Recent Articles
1.
Vikelis M, Kourlaba G, Barba L, Bilias K, Barbalia E, Solakidi A, et al.
Front Neurol
. 2025 Mar;
16:1558014.
PMID: 40066304
Introduction: Migraine is a chronic, debilitating neurological disease affecting more than 1 billion patients, worldwide. Even though migraines are not life-threatening, they have profound effects on individuals, families, and society....
2.
Kourlaba G, Vikelis M, Karapanayiotides T, Solakidi A, Trafalis D, Lioliou K, et al.
Front Neurol
. 2025 Mar;
16:1556808.
PMID: 40040919
Introduction: Migraine is a chronic, debilitating neurological disorder affecting billions worldwide. While not life-threatening, migraine patients experience significant unmet needs in diagnosis and management. Addressing these challenges could result in...
3.
Varna D, Geromichalos G, Dalezis P, Hatzidimitriou A, Psomas G, Zachariadis G, et al.
Eur J Med Chem
. 2024 Aug;
277:116746.
PMID: 39146831
Metal complexes showing dual activity against cancer and bacterial infections are currently the focus of significant interest for their potential in treating life-threatening diseases. Aiming to investigate the impact of...
4.
Varna D, Geromichalos G, Gioftsidou D, Tzimopoulos D, Hatzidimitriou A, Dalezis P, et al.
J Inorg Biochem
. 2024 Jan;
252:112472.
PMID: 38215535
Group 11 metal complexes exhibit promising antibacterial and anticancer properties which can be further enhanced by appropriate ligands. Herein, a series of mononuclear thioamidato Cu(I) and Ag(I) complexes bearing either...
5.
Leonidis G, Dalezis P, Trafalis D, Beis D, Giardoglou P, Koukiali A, et al.
ACS Omega
. 2021 Nov;
6(42):28379-28393.
PMID: 34723035
In the present study, SRPIN803 and c(RGDyK)-SRPIN803 hybrid compounds were efficiently synthesized and evaluated for their stability in human plasma and buffers of pH 7.4 and 5.2. The hybrids were...
6.
Chatzisideri T, Dalezis P, Leonidis G, Bousis S, Trafalis D, Bianchini F, et al.
Future Med Chem
. 2021 Apr;
13(10):877-895.
PMID: 33858195
Cucurbitacins (CUCUs) are triterpenoids known to display potent cytotoxic effects; however, their clinical application is limited due to poor pharmacokinetics and systemic toxicity. This work focuses on the development of...
7.
Ozdogan M, Papadopoulou E, Tsoulos N, Tsantikidi A, Mariatou V, Tsaousis G, et al.
BMC Med Genomics
. 2021 Apr;
14(1):105.
PMID: 33853586
Background: Tumor molecular profile analysis by Next Generation Sequencing technology is currently widely applied in clinical practice and has enabled the detection of predictive biomarkers of response to targeted treatment....
8.
Anastasiadou D, Geromichalou E, Tsavea E, Psomas G, Hatzidimitriou A, Kalogiannis S, et al.
J Inorg Biochem
. 2020 Jul;
210:111167.
PMID: 32653633
Herein we report on the synthesis and molecular structures of six silver(I) mixed-ligand complexes containing a heterocyclic thioamide [4-phenyl-imidazole-2-thione (phimtH) or 2,2,5,5-tetramethyl-imidazolidine-4-thione (tmimdtH)] and a tertiary arylphosphane [triphenylphosphine (PPh), tri-o-tolylphosphane...
9.
Trafalis D, Dalezis P, Geromichalou E, Sagredou S, Sflakidou E, Voura M, et al.
Future Med Chem
. 2019 Nov;
12(1):19-35.
PMID: 31729254
Steroidal prodrugs of nitrogen mustards such as estramustine and prednimustine have proven effective anticancer agents in clinical use since the 1970s. In this work, we aimed to develop steroidal prodrugs...
10.