Dimitri Krainc
Overview
Explore the profile of Dimitri Krainc including associated specialties, affiliations and a list of published articles.
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159
Citations
16809
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Recent Articles
1.
Gao G, Shi Y, Deng H, Krainc D
Nat Commun
. 2025 Feb;
16(1):1982.
PMID: 40011434
Dysregulation of mitochondrial function has been implicated in Parkinson's disease (PD), but the role of mitochondrial metabolism in disease pathogenesis remains to be elucidated. Using an unbiased metabolomic analysis of...
2.
Cisterna-Garcia A, Bustos B, Bandres-Ciga S, Leal T, Sarihan E, Jok C, et al.
Brain
. 2024 Dec;
PMID: 39657708
Genome-wide association studies (GWAS) have increased our understanding of Parkinson's disease (PD) genetics by identifying common disease-associated variants. However, much of the heritability remains unaccounted for and we hypothesized that...
3.
Landoulsi Z, Ashok Kumar Sreelatha A, Schulte C, Bobbili D, Montanucci L, Leu C, et al.
medRxiv
. 2024 Sep;
PMID: 39228715
Objective: Our study investigates the impact of copy number variations (CNVs) on Parkinson's disease (PD) pathogenesis using genome-wide data, aiming to uncover novel genetic mechanisms and improve the understanding of...
4.
Domenighetti C, Sugier P, Ashok Kumar Sreelatha A, Schulte C, Grover S, Portugal B, et al.
Neurology
. 2024 Jul;
103(3):e209620.
PMID: 38986057
Background And Objectives: The role of body mass index (BMI) in Parkinson disease (PD) is unclear. Based on the Comprehensive Unbiased Risk Factor Assessment for Genetics and Environment in PD...
5.
Song P, Krainc D
Mov Disord
. 2024 Jun;
39(8):1282-1288.
PMID: 38858837
Parkinson's disease (PD) is characterized by preferential degeneration of midbrain dopaminergic neurons that contributes to its typical clinical manifestation. Mutations in the parkin gene (PARK2) represent a relatively common genetic...
6.
Coukos R, Krainc D
Nat Rev Neurosci
. 2024 Apr;
25(6):393-413.
PMID: 38600347
Parkinson disease (PD) is a neurodegenerative disorder marked by the preferential dysfunction and death of dopaminergic neurons in the substantia nigra. The onset and progression of PD is influenced by...
7.
Wyse R, Isaacs T, Barker R, Cookson M, Dawson T, Devos D, et al.
J Parkinsons Dis
. 2024 Apr;
14(4):657-666.
PMID: 38578902
In 2011, the UK medical research charity Cure Parkinson's set up the international Linked Clinical Trials (iLCT) committee to help expedite the clinical testing of potentially disease modifying therapies for...
8.
Keller Sarmiento I, Bustos B, Blackburn J, Hac N, Ruzhnikov M, Monroe M, et al.
Mov Disord
. 2024 Apr;
39(7):1231-1236.
PMID: 38576116
Background: FRMD5 variants were recently identified in patients with developmental delay, ataxia, and eye movement abnormalities. Objectives: We describe 2 patients presenting with childhood-onset ataxia, nystagmus, and seizures carrying pathogenic...
9.
Gonzalez-Latapi P, Bustos B, Dong S, Lubbe S, Simuni T, Krainc D
Ann Neurol
. 2024 Apr;
95(6):1162-1172.
PMID: 38563317
Objective: To characterize DNA methylation (DNAm) differences between sporadic Parkinson's disease (PD) and healthy control (HC) individuals enrolled in the Parkinson's Progression Markers Initiative (PPMI). Methods: Using whole blood, we...
10.
Ross M, Krainc D, Guo M, Mouradian M, Ratan R
Ann Neurol
. 2024 Mar;
95(5):825-826.
PMID: 38436546
No abstract available.