Dimitra Tsavachidou
Overview
Explore the profile of Dimitra Tsavachidou including associated specialties, affiliations and a list of published articles.
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8
Citations
416
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Recent Articles
1.
Chen H, Fu T, Suh W, Tsavachidou D, Wen S, Gao J, et al.
Cancer Immunol Res
. 2014 Apr;
2(2):167-76.
PMID: 24778280
The transcription factor T-bet controls the Th1 genetic program in T cells for effective antitumor responses. Anti-CTLA-4 immunotherapy elicits dramatic antitumor responses in mice and in human patients; however, factors...
2.
Guo H, Liu W, Ju Z, Tamboli P, Jonasch E, Mills G, et al.
Proteome Sci
. 2012 Sep;
10(1):56.
PMID: 23006314
Unlabelled: Introduction: Protein extraction from formalin-fixed paraffin-embedded (FFPE) tissues is challenging due to extensive molecular crosslinking that occurs upon formalin fixation. Reverse-phase protein array (RPPA) is a high-throughput technology, which...
3.
Efstathiou E, Titus M, Tsavachidou D, Tzelepi V, Wen S, Hoang A, et al.
J Clin Oncol
. 2011 Dec;
30(6):637-43.
PMID: 22184395
Purpose: Persistent androgen signaling is implicated in castrate-resistant prostate cancer (CRPC) progression. This study aimed to evaluate androgen signaling in bone marrow-infiltrating cancer and testosterone in blood and bone marrow...
4.
Cheong J, Park E, Liang J, Dennison J, Tsavachidou D, Nguyen-Charles C, et al.
Mol Cancer Ther
. 2011 Oct;
10(12):2350-62.
PMID: 21992792
Tumor cell proliferation requires both growth signals and sufficient cellular bioenergetics. The AMP-activated protein kinase (AMPK) pathway seems dominant over the oncogenic signaling pathway suppressing cell proliferation. This study investigated...
5.
Tsavachidou D, McDonnell T, Wen S, Wang X, Vakar-Lopez F, Pisters L, et al.
J Natl Cancer Inst
. 2009 Feb;
101(5):306-20.
PMID: 19244175
Background: Secondary analyses of two randomized, controlled phase III trials demonstrated that selenium and vitamin E could reduce prostate cancer incidence. To characterize pharmacodynamic and gene expression effects associated with...
6.
Kim J, Jonasch E, Alexander A, Short J, Cai S, Wen S, et al.
Clin Cancer Res
. 2009 Jan;
15(1):81-90.
PMID: 19118035
Purpose: p27 localization and expression has prognostic and predictive value in cancer. Little is known regarding expression patterns of p27 in renal cell carcinoma (RCC) or how p27 participates in...
7.
Tsavachidou D, Coleman M, Athanasiadis G, Li S, Licht J, Olson M, et al.
Cancer Res
. 2004 Aug;
64(16):5556-9.
PMID: 15313890
BRAF mutations result in constitutively active BRAF kinase activity and increased extracellular signal-regulated kinase (ERK) signaling and cell proliferation. Initial studies have shown that BRAF mutations occur at a high...
8.
Tsavachidou D, Liebman M
J Am Med Inform Assoc
. 2002 Sep;
9(5):461-71.
PMID: 12223498
The analytical representation and simulation of complex molecular pathways can contribute to understanding and evaluating physiological as well as pathological processes. We are interested in modeling the processes of menopause...