Diego Altomare
Overview
Explore the profile of Diego Altomare including associated specialties, affiliations and a list of published articles.
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31
Citations
413
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Recent Articles
1.
Samani S, Barlow S, Freeburg L, Catherwood G, Churillo A, Jones T, et al.
Am J Physiol Heart Circ Physiol
. 2024 Sep;
327(5):H1272-H1285.
PMID: 39240258
Left ventricular pressure overload (LVPO) can lead to heart failure with a preserved ejection fraction (HFpEF) and LV chamber stiffness (LV ) is a hallmark. This project tested the hypothesis...
2.
Cui B, Aksenova M, Sikirzhytskaya A, Odhiambo D, Korunova E, Sikirzhytski V, et al.
J Neurovirol
. 2024 Jun;
30(4):337-352.
PMID: 38884890
HIV-associated neurological disorder (HAND) is a serious complication of HIV infection marked by neurotoxicity induced by viral proteins like Tat. Substance abuse exacerbates neurocognitive impairment in people living with HIV....
3.
Choi A, Jenkins-Lane L, Barton W, Kumari A, Lancaster C, Raulerson C, et al.
Cell Commun Signal
. 2024 Feb;
22(1):128.
PMID: 38360757
In pathologies including cancer, aberrant Transforming Growth Factor-β (TGF-β) signaling exerts profound tumor intrinsic and extrinsic consequences. Intense clinical endeavors are underway to target this pathway. Central to the success...
4.
Cui B, Aksenova M, Sikirzhytskaya A, Odhiambo D, Korunova E, Sikirzhytski V, et al.
bioRxiv
. 2023 Oct;
PMID: 37808776
HIV-associated neurological disorder (HAND) is a serious complication of HIV infection, marked by neurotoxicity induced by viral proteins like Tat. Substance abuse exacerbates neurocognitive impairment in people living with HIV....
5.
Choi A, Jenkins-Lane L, Barton W, Kumari A, Lancaster C, Raulerson C, et al.
bioRxiv
. 2023 Sep;
PMID: 37693479
In pathologies such as cancer, aberrant Transforming Growth Factor-β (TGF-β) signaling exerts profound tumor intrinsic and extrinsic consequences. Intense clinical endeavors are underway to target this pivotal pathway. Central to...
6.
Chen M, Li J, Zhang L, Wang L, Cheng C, Ji H, et al.
Nucleic Acids Res
. 2023 Jun;
51(14):7288-7313.
PMID: 37378433
We have conducted a detailed transcriptomic, proteomic and phosphoproteomic analysis of CDK8 and its paralog CDK19, alternative enzymatic components of the kinase module associated with transcriptional Mediator complex and implicated...
7.
Shonibare Z, Monavarian M, OConnell K, Altomare D, Shelton A, Mehta S, et al.
Cell Rep
. 2022 Jul;
40(4):111066.
PMID: 35905726
Growth factors in tumor environments are regulators of cell survival and metastasis. Here, we reveal the dichotomy between TGF-β superfamily growth factors BMP and TGF-β/activin and their downstream SMAD effectors....
8.
Craig S, Baxter M, Chapagai D, Stafford J, Nurmemmedov E, Altomare D, et al.
Eur J Med Chem
. 2021 Nov;
227:113926.
PMID: 34735919
Polo-like kinase 1 (PLK1) is a serine/threonine-protein kinase involved in cell cycle regulation and mitotic progression. Studies have shown that PLK1 is upregulated in many tumors and high levels are...
9.
Lucius M, Ji H, Altomare D, Doran R, Torkian B, Havighorst A, et al.
BMC Genomics
. 2021 Sep;
22(1):662.
PMID: 34521341
Background: Deer mice (genus Peromyscus) are the most common rodents in North America. Despite the availability of reference genomes for some species, a comprehensive database of polymorphisms, especially in those...
10.
Aladhami A, Unger C, Ennis S, Altomare D, Ji H, Hope 3rd M, et al.
FASEB J
. 2021 Jun;
35(7):e21665.
PMID: 34131955
The pro-inflammatory cytokine, tumor necrosis factor-alpha (TNF-α), has been suggested to be a key factor in the induction of obesity-associated metabolic dysfunction. However, the role that macrophage-derived TNF-α has on...