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Dibyendu Dutta

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Articles 47
Citations 256
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Recent Articles
11.
Zerdan M, Kassab J, Meouchy P, Haroun E, Nehme R, Zerdan M, et al.
Cancers (Basel) . 2022 Oct; 14(19). PMID: 36230736
The lung is home to a dynamic microbial population crucial to modulating immune balance. Interest in the role of the lung microbiota in disease pathogenesis and treatment has exponentially increased....
12.
Nasr D, Moein M, Niforatos S, Nasr S, Ombada M, Khokhar F, et al.
J Clin Med . 2022 May; 11(10). PMID: 35628853
Many broad-spectrum antibiotics (BSA) alter the intestinal microbiome that regulates adaptive immune responses. We hypothesized that BSA use before and early after kidney transplant may affect acute graft rejection (AGR)....
13.
Jafri F, Seong G, Jang T, Cimpeanu E, Poplawska M, Dutta D, et al.
Ann Hematol . 2022 May; 101(8):1645-1654. PMID: 35568758
Oxidative stress is a major contributor to the pathophysiology of sickle cell disease (SCD) including hemolysis and vaso-occlusive crisis (VOC). L-glutamine is a conditionally essential amino acid with important roles,...
14.
Poplawska M, Dutta D, Jayaram M, Chong N, Salifu M, Lim S
Ann Hematol . 2022 Feb; 101(5):1009-1013. PMID: 35166891
Based on previous studies showing abnormalities in the intestinal pathophysiology characterized by disruption in the gut barrier functions, and alteration in the intestinal microbial load and composition, we set out...
15.
Zerdan M, Niforatos S, Nasr S, Nasr D, Ombada M, John S, et al.
Cancers (Basel) . 2022 Feb; 14(3). PMID: 35158960
Understanding of the importance of the normal intestinal microbial community in regulating microbial homeostasis, host metabolism, adaptive immune responses, and gut barrier functions has opened up the possibility of manipulating...
16.
Leibovitch J, Tambe A, Cimpeanu E, Poplawska M, Jafri F, Dutta D, et al.
Blood Rev . 2022 Jan; 53:100925. PMID: 34991920
For more than two decades, hydroxyurea was the only therapeutic agent approved by the Food and Drug Administration (FDA) for sickle cell disease (SCD). Although curative allogeneic hematopoietic stem cell...
17.
Poplawska M, Dutta D, Lee Y, Lim S
Mol Ther Oncolytics . 2021 Dec; 23:378-386. PMID: 34853809
Due to the vague symptomatology of the disease and a lack of effective screening methods, most patients with epithelial ovarian cancer (EOC) present late in their disease. Despite advances in...
18.
Poplawska M, Dutta D, Jayaram M, Salifu M, Chong N, Lim S
Br J Haematol . 2021 Oct; 196(3):777-780. PMID: 34632582
We showed in the present study that, not unlike in adult patients with sickle cell disease (SCD), Townes mice exhibit increases in serum intestinal fatty acid binding proteins and lipopolysaccharides...
19.
Jang T, Mo G, Stewart C, Khoury L, Ferguson N, Egini O, et al.
Cell Transplant . 2021 Oct; 30:9636897211046559. PMID: 34628962
Hematopoietic stem cell transplant (HSCT) is the only cure for patients with sickle cell disease (SCD). Although most SCD patients experience progressive end-organ damage and shortened lifespans, not all patients...
20.
Jang T, Poplawska M, Cimpeanu E, Mo G, Dutta D, Lim S
J Transl Med . 2021 Sep; 19(1):397. PMID: 34544432
Painful vaso-occlusive crisis (VOC) remains the most common reason for presenting to the Emergency Department and hospitalization in patients with sickle cell disease (SCD). Although two new agents have been...