Dianne K Anestis
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Explore the profile of Dianne K Anestis including associated specialties, affiliations and a list of published articles.
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11
Citations
28
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Recent Articles
1.
Rankin G, Racine C, Valentovic M, Anestis D
Int J Mol Sci
. 2021 Jan;
22(1).
PMID: 33396638
The current study was designed to explore the in vitro nephrotoxic potential of four 3,5-dichloroaniline (3,5-DCA) metabolites (3,5-dichloroacetanilide, 3,5-DCAA; 3,5-dichlorophenylhydroxylamine, 3,5-DCPHA; 2-amino-4,6-dichlorophenol, 2-A-4,6-DCP; 3,5-dichloronitrobenzene, 3,5-DCNB) and to determine the renal...
2.
Role of Free Radicals and Biotransformation in Trichloronitrobenzene-Induced Nephrotoxicity In Vitro
Rankin G, Tyree C, Pope D, Tate J, Racine C, Anestis D, et al.
Int J Mol Sci
. 2017 Jun;
18(6).
PMID: 28561793
This study determined the comparative nephrotoxic potential of four trichloronitrobenzenes (TCNBs) (2,3,4-; 2,4,5-; 2,4,6-; and 3,4,5-TCNB) and explored the effects of antioxidants and biotransformation inhibitors on TCNB-induced cytotoxicity in isolated...
3.
Rankin G, Sweeney A, Racine C, Ferguson T, Preston D, Anestis D
Chem Biol Interact
. 2014 Dec;
222:126-32.
PMID: 25446496
Chlorinated anilines are nephrotoxicants both in vivo and in vitro. The mechanism of chloroaniline nephrotoxicity may occur via more than one mechanism, but aminochlorophenol metabolites appear to contribute to the...
4.
Racine C, Ward D, Anestis D, Ferguson T, Preston D, Rankin G
Int J Mol Sci
. 2014 Nov;
15(11):20900-12.
PMID: 25402648
Chloroanilines are widely used in the manufacture of drugs, pesticides and industrial intermediates. Among the trichloroanilines, 3,4,5-trichloroaniline (TCA) is the most potent nephrotoxicant in vivo. The purpose of this study...
5.
Rankin G, Hong S, Anestis D, Ball J, Valentovic M, Graffeo V
Toxicology
. 2012 Jun;
300(1-2):92-9.
PMID: 22706168
The agricultural fungicide N-(3,5-dichlorophenyl)succinimide (NDPS) can induce marked nephrotoxicity in rats following a single intraperitoneal (ip) administration of 0.4mmol/kg or greater. Although NDPS induces direct renal proximal tubular toxicity, a...
6.
Rankin G, Hong S, Anestis D
J Appl Toxicol
. 2008 Apr;
28(7):867-73.
PMID: 18418842
The agricultural fungicide N-(3,5-dichlorophenyl)succinimide (NDPS) is a more potent nephrotoxicant in female rats than in males. Similarly, nephrotoxicant NDPS metabolites studied to date in male and female rats have also...
7.
Rankin G, Hong S, Anestis D, Ball J, Valentovic M
Toxicology
. 2008 Feb;
245(1-2):123-9.
PMID: 18243470
4-Amino-2,6-dichlorophenol (ADCP) is a potent acute nephrotoxicant in vivo inducing prominent renal corticomedullary necrosis. In vitro, ADCP exposure increases lactate dehydrogenase (LDH) release from rat renal cortical slices at 0.05...
8.
Rankin G, Racine C, Sweeney A, Kraynie A, Anestis D, Barnett J
Environ Toxicol
. 2008 Jan;
23(4):435-42.
PMID: 18214888
Propanil is a postemergence herbicide used primarily in rice and wheat production in the United States. The reported toxicities for propanil exposure include methemoglobinemia, immunotoxicity, and nephrotoxicity. A major metabolite...
9.
Rankin G, Anestis D, Valentovic M, Sun H, Triest W
Toxicology
. 2007 Aug;
240(1-2):38-47.
PMID: 17728037
The agricultural fungicide N-(3,5-dichlorophenyl)succinimide (NDPS) induces nephrotoxicity characterized as polyuric renal failure and mediated via metabolites arising from oxidation of the succinimide ring. Recent findings have suggested that the stereochemical...
10.
Rankin G, Hong S, Anestis D, Henderson T, Ball J, Valentovic M, et al.
J Toxicol Environ Health A
. 2002 Apr;
65(7):539-56.
PMID: 11939711
The agricultural fungicide N-(3,5-dichlorophenyl)succinimide (NDPS) induces nephrotoxicity in mammals characterized as polyuric renal failure and proximal tubular necrosis. Recent studies have suggested that NDPS-induced nephrotoxicity may be mediated by metabolites...