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Diane Ordway

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Citations 1424
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Recent Articles
1.
Bai X, Verma D, Garcia C, Musheyev A, Kim K, Fornis L, et al.
Front Cell Infect Microbiol . 2023 Nov; 13:1216492. PMID: 37965256
Introduction: A strong epidemiologic link exists between cigarette smoke (CS) exposure and susceptibility to tuberculosis (TB). Macrophage and murine studies showed that CS and nicotine impair host-protective immune cells against...
2.
Ochsner U, De Groote M, Jarvis T, Liu H, Youmans T, Hoang T, et al.
Tuberculosis (Edinb) . 2022 Dec; 138:102288. PMID: 36470124
The benzothiazole amide CRS0393 demonstrated excellent in vitro activity against nontuberculous mycobacteria (NTM), including M. abscessus isolates from cystic fibrosis (CF) patients, with minimum inhibitory concentrations (MICs) of ≤0.03-0.5 μg/mL....
3.
Schenkel A, Mitchell J, Cool C, Bai X, Groshong S, Koelsch T, et al.
Immune Netw . 2022 Jul; 22(3):e27. PMID: 35799709
Little is known of the lung cellular immunophenotypes in patients with non-tuberculous mycobacterial lung disease (NTM-LD). Flow-cytometric analyses for the major myeloid and lymphoid cell subsets were performed in less-...
4.
Bai X, Buckle A, Vladar E, Janoff E, Khare R, Ordway D, et al.
Sci Rep . 2022 Apr; 12(1):6466. PMID: 35440617
No abstract available.
5.
Bai X, Buckle A, Vladar E, Janoff E, Khare R, Ordway D, et al.
Sci Rep . 2022 Mar; 12(1):5207. PMID: 35338216
The cell surface serine protease Transmembrane Protease 2 (TMPRSS2) is required to cleave the spike protein of SARS-CoV-2 for viral entry into cells. We determined whether negatively-charged heparin enhanced TMPRSS2...
6.
Larsen S, Reese V, Pecor T, Berube B, Cooper S, Brewer G, et al.
Sci Rep . 2021 Apr; 11(1):9040. PMID: 33907221
The nontuberculous mycobacteria (NTM) Mycobacterium avium is a clinically significant pathogen that can cause a wide range of maladies, including tuberculosis-like pulmonary disease. An immunocompromised host status, either genetically or...
7.
Bai X, Hippensteel J, Leavitt A, Maloney J, Beckham D, Garcia C, et al.
Med Hypotheses . 2020 Nov; 146:110394. PMID: 33239231
No definitive treatment for COVID-19 exists although promising results have been reported with remdesivir and glucocorticoids. Short of a truly effective preventive or curative vaccine against SARS-CoV-2, it is becoming...
8.
Jain P, Garing S, Verma D, Saranathan R, Clute-Reinig N, Gadwa J, et al.
J Bacteriol . 2020 Sep; 202(22). PMID: 32900827
Phenotypic testing for drug susceptibility of is critical to basic research and managing the evolving problem of antimicrobial resistance in tuberculosis management, but it remains a specialized technique to which...
9.
Raynaud C, Daher W, Roquet-Baneres F, Johansen M, Stec J, Onajole O, et al.
Antimicrob Agents Chemother . 2020 Feb; 64(5). PMID: 32041716
New drugs or therapeutic combinations are urgently needed against Previously, we demonstrated the potent activity of indole-2-carboxamides 6 and 12 against We show here that these compounds act synergistically with...
10.
De P, Shi L, Boot C, Ordway D, McNeil M, Chatterjee D
ACS Infect Dis . 2019 Nov; 6(2):291-301. PMID: 31762254
lipoarabinomannan (LAM) is a biomarker for active tuberculosis (TB) disease. The presence of LAM in the urine of TB patients, whether HIV positive or negative, has been validated by a...