Diahann T S L Jansen
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Explore the profile of Diahann T S L Jansen including associated specialties, affiliations and a list of published articles.
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16
Citations
249
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Recent Articles
11.
Jansen D, Ramnoruth N, Loh K, Rossjohn J, Reid H, Nel H, et al.
Front Immunol
. 2018 Feb;
9:8.
PMID: 29403492
With the advent of novel strategies to induce tolerance in autoimmune and autoimmune-like conditions, clinical trials of antigen-specific tolerizing immunotherapy have become a reality. Besides safety, it will be essential...
12.
Jansen D, El Bannoudi H, Arens R, Habets K, Hameetman M, Huizinga T, et al.
Arthritis Res Ther
. 2015 Aug;
17:220.
PMID: 26290328
Introduction: Abatacept is a fusion protein of human cytotoxic T-lymphocyte-associated protein (CTLA)-4 and the Fc portion of human immunoglobulin G1 (IgG1). It is believed to be effective in the treatment...
13.
Franke L, El Bannoudi H, Jansen D, Kok K, Trynka G, Diogo D, et al.
Eur J Hum Genet
. 2015 May;
24(2):263-70.
PMID: 25966632
Segmental duplications (SDs) comprise about 5% of the human genome and are enriched for immune genes. SD loci often show copy numbers variations (CNV), which are difficult to tag with...
14.
Heemst J, Jansen D, Polydorides S, Moustakas A, Bax M, Feitsma A, et al.
Nat Commun
. 2015 May;
6:6681.
PMID: 25942574
The HLA locus is the strongest risk factor for anti-citrullinated protein antibody (ACPA)(+) rheumatoid arthritis (RA). Despite considerable efforts in the last 35 years, this association is poorly understood. Here...
15.
Jansen D, Hameetman M, van Bergen J, Huizinga T, van der Heijde D, Toes R, et al.
Rheumatology (Oxford)
. 2014 Oct;
54(4):728-35.
PMID: 25288779
Objective: Increased numbers of IL-17-producing CD4(+) T cells have been observed in AS. However, it is not known whether these CD4(+) T cells are already present in early disease or...
16.
Stoop J, Liu B, Shi J, Jansen D, Hegen M, Huizinga T, et al.
PLoS One
. 2014 Jul;
9(7):e102163.
PMID: 25025869
Objective: The immune response to post-translationally modified antigens is a key characteristic of rheumatoid arthritis. Carbamylation is such a posttranslational modification. Recently, we demonstrated that autoantibodies recognizing carbamylated proteins are...
17.
Kleijwegt F, Jansen D, Teeler J, Joosten A, Laban S, Nikolic T, et al.
Eur J Immunol
. 2012 Oct;
43(1):85-92.
PMID: 23042025
Type 1 diabetes is a T-cell-mediated autoimmune disease in which autoreactive CD8(+) T cells destroy the insulin-producing pancreatic beta cells. Vitamin D3 and dexamethasone-modulated dendritic cells (Combi-DCs) loaded with islet...
18.
Phylipsen M, Yamsri S, Treffers E, Jansen D, Kanhai W, Boon E, et al.
Prenat Diagn
. 2012 Apr;
32(6):578-87.
PMID: 22517437
Objective: The aim of this study was to develop a pyrophosphorolysis-activated polymerization (PAP) assay for non-invasive prenatal diagnosis (NIPD) of β-thalassemia major and sickle-cell disease (SCD). PAP is able to...