Dharshan Sivaraj
Overview
Explore the profile of Dharshan Sivaraj including associated specialties, affiliations and a list of published articles.
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Articles
43
Citations
490
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Recent Articles
1.
Barrera J, Lakhlani D, Francis S, Maheta B, Gonzalez C, Nino G, et al.
J Plast Reconstr Aesthet Surg
. 2025 Feb;
102:176-184.
PMID: 39933364
Background: Implant-based breast reconstruction has a higher infection risk than cosmetic augmentation, leading to routine prophylactic antibiotic use. We previously found extended prophylaxis reduced infections during the first-stage reconstruction with...
2.
Hostler A, Hahn W, Hu M, Rennert R, Fischer K, Barrera J, et al.
FASEB J
. 2024 Dec;
38(24):e70210.
PMID: 39698751
C-X-C motif chemokine ligand 12 (CXCL12; Stromal Cell-Derived Factor 1 [SDF-1]), most notably known for its role in embryogenesis and hematopoiesis, has been implicated in tumor pathophysiology and neovascularization. However,...
3.
Granoski M, Fischer K, Hahn W, Sivaraj D, Kussie H, Quintero F, et al.
Front Physiol
. 2024 Oct;
15:1427113.
PMID: 39473610
Introduction: The FOXC2 transcription factor has been tied to a wide range of disease states, serving as a promising prognostic biomarker associated with aggressive basal-like human breast cancers (increased cancer...
4.
Perrault D, Chattopadhyay A, Sivaraj D, Wan D, Chen K, Gurtner G, et al.
Ann Surg Open
. 2024 Jun;
5(1):e372.
PMID: 38883943
In this study, we present the first-in-human use of topical deferoxamine (DFO) in the treatment of a beta-thalassemia wound. We elected to use DFO on a patient that suffered from...
5.
Fischer K, Henn D, Zhao E, Sivaraj D, Litmanovich B, Hahn W, et al.
Tissue Eng Part A
. 2024 May;
30(23-24):752-765.
PMID: 38753711
Elevated shear stress (ESS) induces vascular remodeling in veins exposed to arterial blood flow, which can lead to arteriovenous (AV) fistula failure. The molecular mechanisms driving remodeling have not been...
6.
Kussie H, Hahn W, Sivaraj D, Quintero F, Knochel A, Alfsharif A, et al.
Adv Wound Care (New Rochelle)
. 2024 Feb;
13(4):155-166.
PMID: 38299969
Given the significant economic, health care, and personal burden of acute and chronic wounds, we investigated the dose dependent wound healing mechanisms of two derived compounds: avenanthramide (AVN) and β-Glucan....
7.
Padmanabhan J, Chen K, Sivaraj D, Henn D, Kuehlmann B, Kussie H, et al.
Nat Biomed Eng
. 2023 Sep;
7(11):1419-1436.
PMID: 37749310
Small animals do not replicate the severity of the human foreign-body response (FBR) to implants. Here we show that the FBR can be driven by forces generated at the implant...
8.
Henn D, Zhao D, Sivaraj D, Trotsyuk A, Bonham C, Fischer K, et al.
Nat Commun
. 2023 Aug;
14(1):4729.
PMID: 37550295
Chronic wounds impose a significant healthcare burden to a broad patient population. Cell-based therapies, while having shown benefits for the treatment of chronic wounds, have not yet achieved widespread adoption...
9.
Henn D, Trotsyuk A, Barrera J, Sivaraj D, Chen K, Mittal S, et al.
Plast Reconstr Surg
. 2023 Jun;
152(1):239-249.
PMID: 37382921
Although robotic surgery has been routinely established in other surgical disciplines, robotic technologies have been less readily adopted in plastic surgery. Despite a strong demand for innovation and cutting-edge technology...
10.
Griffin M, Talbott H, Guardino N, Guo J, Spielman A, Chen K, et al.
bioRxiv
. 2023 Apr;
PMID: 37066136
While past studies have suggested that plasticity exists between dermal fibroblasts and adipocytes, it remains unknown whether fat actively contributes to fibrosis in scarring. We show that adipocytes convert to...