Devendra K Rai
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Explore the profile of Devendra K Rai including associated specialties, affiliations and a list of published articles.
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36
Citations
1203
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Recent Articles
1.
Tuttle J, Allais C, Allerton C, Anderson A, Arcari J, Aschenbrenner L, et al.
J Med Chem
. 2025 Feb;
PMID: 40019854
In early 2020, severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) infections leading to COVID-19 disease reached a global level leading to the World Health Organization (WHO) declaration of a...
2.
Rosales R, McGovern B, Rodriguez M, Leiva-Rebollo R, Diaz-Tapia R, Benjamin J, et al.
Antiviral Res
. 2024 Jul;
230:105970.
PMID: 39067667
Variants of SARS-CoV-2 pose significant challenges in public health due to their increased transmissibility and ability to evade natural immunity, vaccine protection, and monoclonal antibody therapeutics. The emergence of the...
3.
Zhu Y, Yurgelonis I, Noell S, Yang Q, Guan S, Li Z, et al.
Sci Adv
. 2024 Jul;
10(30):eadl4013.
PMID: 39047088
To facilitate the detection and management of potential clinical antiviral resistance, in vitro selection of drug-resistant severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) against the virus M inhibitor nirmatrelvir (Paxlovid...
4.
Allerton C, Arcari J, Aschenbrenner L, Avery M, Bechle B, Behzadi M, et al.
J Med Chem
. 2024 Apr;
67(16):13550-13571.
PMID: 38687966
Despite the record-breaking discovery, development and approval of vaccines and antiviral therapeutics such as Paxlovid, coronavirus disease 2019 (COVID-19) remained the fourth leading cause of death in the world and...
5.
Mishra-Gorur K, Barak T, Kaulen L, Henegariu O, Jin S, Aguilera S, et al.
Proc Natl Acad Sci U S A
. 2024 Mar;
121(12):e2319578121.
PMID: 38466853
No abstract available.
6.
Mishra-Gorur K, Barak T, Kaulen L, Henegariu O, Jin S, Aguilera S, et al.
Proc Natl Acad Sci U S A
. 2023 Apr;
120(16):e2214997120.
PMID: 37043537
While somatic variants of (Tumor necrosis factor receptor-associated factor 7) underlie anterior skull-base meningiomas, here we report the inherited mutations of that cause congenital heart defects. We show that TRAF7...
7.
Zhu Y, Binder J, Yurgelonis I, Rai D, Lazarro S, Costales C, et al.
Antiviral Res
. 2022 Oct;
208:105429.
PMID: 36208677
Vero cells are widely used for antiviral tests and virology research for SARS-CoV-2 as well as viruses from various other families. However, Vero cells generally express high levels of multi-drug...
8.
Barak T, Ristori E, Ercan-Sencicek A, Miyagishima D, Nelson-Williams C, Dong W, et al.
Nat Med
. 2021 Dec;
27(12):2165-2175.
PMID: 34887573
Intracranial aneurysm (IA) rupture leads to subarachnoid hemorrhage, a sudden-onset disease that often causes death or severe disability. Although genome-wide association studies have identified common genetic variants that increase IA...
9.
Owen D, Allerton C, Anderson A, Aschenbrenner L, Avery M, Berritt S, et al.
Science
. 2021 Nov;
374(6575):1586-1593.
PMID: 34726479
The worldwide outbreak of COVID-19 caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become a global pandemic. Alongside vaccines, antiviral therapeutics are an important part of the healthcare...
10.
Kloc A, Rai D, Gladue D, Schafer E, Kenney M, Rieder E
J Virol
. 2020 Jun;
94(17).
PMID: 32581111
Many RNA viruses encode a proof-reading deficient, low-fidelity RNA-dependent polymerase (RdRp), which generates genetically diverse populations that can adapt to changing environments and thwart antiviral therapies. 3D, the RdRp of...