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Derseree Archary

Explore the profile of Derseree Archary including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 42
Citations 1098
Followers 0
Related Specialties
General Medicine
Infectious Diseases
Allergy & Immunology
Top 10 Co-Authors
Salim S Abdool Karim
Aida Sivro
Sinaye Ngcapu
Quarraisha Abdool Karim
Natasha Samsunder
Nigel Garrett
Lenine J P Liebenberg
Jo-Ann S Passmore
Sharana Mahomed
Cheryl Baxter
Published In
Front Immunol
Sci Rep
BMJ Open
Clin Infect Dis
BMC Immunol
Affiliations
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Recent Articles
1.
Drug transporter mRNA expression and genital inflammation in South African women on oral pre-exposure prophylaxis (PrEP)
Zondo N, Sobia P, Sivro A, Ngcapu S, Mahomed S, Mansoor L, et al.
AIDS Res Ther . 2025 Feb; 22(1):18. PMID: 39955595
Globally HIV remains a major public health problem. In sub-Saharan Africa most new HIV infections occur in adolescent girls and young women. Previously tested antiretroviral drugs as different pre-exposure prophylaxis...
2.
Differences in HIV risk factors between South African adolescents and adult women and their association with sexually transmitted infections
Mkhize P, Mehou-Loko C, Maphumulo N, Radzey N, Abrahams A, Sibeko S, et al.
Sex Transm Infect . 2024 Dec; PMID: 39632075
Objectives: In sub-Saharan Africa, approximately 86% of HIV infections in adolescents aged 15-19 years occur among girls. Their heightened susceptibility is likely influenced by converging sociobehavioural and biological factors, although...
3.
Circulating immunoglobulins and transient lymphocytopenia in a sub-study of CAPRISA 012B, testing HIV monoclonal antibodies in a phase 1 trial
Sobia P, Mahomed S, Sivro A, Paul S, Osman F, Harkoo I, et al.
Sci Rep . 2024 Jun; 14(1):13499. PMID: 38866888
Acute, transient lymphocytopenia, not clinically significant was observed in the CAPRISA 012B phase 1 clinical trial following administration of broadly neutralizing antibodies (bnAb)-CAP256V2LS alone or with VRC07-523LS. Lymphocytopenia was assigned...
4.
Performance of Softcup® menstrual cup and vulvovaginal swab samples for detection and quantification of genital cytokines
Pillay N, Mzobe G, Letsoalo M, Kama A, Mtshali A, Magini S, et al.
J Immunol Methods . 2024 Mar; 528:113656. PMID: 38447801
Cytokines are important mediators of immunity in the female genital tract, and their levels may be associated with various reproductive health outcomes. However, the measurement of cytokines and chemokines in...
5.
SARS-CoV-2 infection in immunosuppression evolves sub-lineages which independently accumulate neutralization escape mutations
Lustig G, Ganga Y, Rodel H, Tegally H, Khairallah A, Jackson L, et al.
Virus Evol . 2024 Feb; 10(1):vead075. PMID: 38361824
One mechanism of variant formation may be evolution during long-term infection in immunosuppressed people. To understand the viral phenotypes evolved during such infection, we tested SARS-CoV-2 viruses evolved from an...
6.
Metronidazole Treatment Failure and Persistent BV Lead to Increased Frequencies of Activated T- and Dendritic-Cell Subsets
Qulu W, Mzobe G, Mtshali A, Letsoalo M, Osman F, San J, et al.
Microorganisms . 2023 Nov; 11(11). PMID: 38004655
Metronidazole (MDZ) treatment failure and bacterial vaginosis (BV) recurrence rates are high among African women. This cohort study identified genital immune parameters associated with treatment response by comparing vaginal microbiota...
7.
Higher plasma interleukin - 6 levels are associated with lung cavitation in drug-resistant tuberculosis
Maseko T, Ngubane S, Letsoalo M, Rambaran S, Archary D, Samsunder N, et al.
BMC Immunol . 2023 Aug; 24(1):26. PMID: 37653422
Background: Lung cavitation is associated with heightened TB transmission and poor treatment outcomes. This study aimed to determine the relationship between systemic inflammation and lung cavitation in drug-resistant TB patients...
8.
Extended safety and tolerability of subcutaneous CAP256V2LS and VRC07-523LS in HIV-negative women: study protocol for the randomised, placebo-controlled double-blinded, phase 2 CAPRISA 012C trial
Mahomed S, Garrett N, Potloane D, Sikazwe I, Capparelli E, Harkoo I, et al.
BMJ Open . 2023 Aug; 13(8):e076843. PMID: 37640457
Introduction: Women-controlled HIV prevention technologies that overcome adherence challenges of available daily oral pre-exposure prophylaxis and give women a choice of options are urgently needed. Broadly neutralising monoclonal antibodies (bnAbs)...
9.
Single-nucleotide polymorphisms in ABC drug transporters alter expression and circulating tenofovir in healthy South African women exposed to pre-exposure prophylaxis
Zondo N, Sobia P, Sivro A, Ngcapu S, Mansoor L, Mahomed S, et al.
Pharmacogenomics . 2023 Jul; 24(11):599-613. PMID: 37503696
We investigated if single-nucleotide polymorphisms (SNPs) in ATP-binding cassette (ABC) drug transporters alter gene expression and tenofovir disposition in South African women taking Truvada for HIV prevention. In 393 women,...
10.
Blood monocyte and dendritic cell profiles among people living with HIV with Mycobacterium tuberculosis co-infection
Rambaran S, Maseko T, Lewis L, Hassan-Moosa R, Archary D, Ngcapu S, et al.
BMC Immunol . 2023 Jul; 24(1):21. PMID: 37480005
Background: Understanding the complex interactions of the immune response mediated by Mycobacterium tuberculosis and HIV co-infection is fundamental to disease biomarker discovery, vaccine, and drug development. Using flow cytometry, we...