Nigel Garrett
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Explore the profile of Nigel Garrett including associated specialties, affiliations and a list of published articles.
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149
Citations
2698
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Recent Articles
1.
Tyers L, Moeser M, Ntuli J, Council O, Zhou S, Spielvogel E, et al.
bioRxiv
. 2025 Feb;
PMID: 39975202
HIV-1 persists as a latent reservoir during suppressive antiretroviral therapy (ART). Viral rebound occurs upon ART interruption, posing a challenge to cure efforts. Characterizing viral populations fuelling rebound is imperative...
2.
Hesselman M, Zeeb M, Rusert P, Pasin C, Mamrosh J, Kariuki S, et al.
Cell Host Microbe
. 2025 Feb;
33(2):279-293.e6.
PMID: 39909038
Identifying HIV-1 envelope (Env) traits associated with neutralization cross-reactivity is crucial for vaccine design. Variable loops 1 and 2 (V1V2), positioned at the Env trimer apex, are key regions linked...
3.
Garrett N, Tapley A, Hudson A, Dadabhai S, Zhang B, Mgodi N, et al.
EClinicalMedicine
. 2025 Feb;
80:103054.
PMID: 39902315
Background: With limited access to mRNA COVID-19 vaccines in lower income countries, and people living with HIV (PLWH) largely excluded from clinical trials, Part A of the multicentre CoVPN 3008...
4.
Schwebs T, Kieninger A, Podpera Tisakova L, Oberbauer V, Berdaguer R, Mtshali A, et al.
Antibiotics (Basel)
. 2025 Jan;
13(12.
PMID: 39766607
: The high recurrence rate of bacterial vaginosis (BV) after antibiotic treatment is at least partially attributed to resistant bacteria. The CAPRISA 083 (CAP083) study investigated the influence of metronidazole...
5.
Council O, Tyers L, Moeser M, Sondgeroth A, Spielvogel E, Richardson B, et al.
J Virol
. 2024 Dec;
99(2):e0097924.
PMID: 39723838
Previous studies have shown that the majority of long-lived cells harboring persistent HIV-1 proviral genomes originates from viruses circulating in the year prior to antiretroviral therapy (ART) initiation, but a...
6.
Garrett N, Reddy T, Yende-Zuma N, Takalani A, Woeber K, Bodenstein A, et al.
PLOS Glob Public Health
. 2024 Dec;
4(12):e0003260.
PMID: 39636838
Limited studies have been conducted on the safety and effectiveness of heterologous COVID-19 vaccine boosting in lower income settings, especially those with high-HIV prevalence., The Sisonke Heterologous mRNA-1273 boost after...
7.
Marsden A, Corcoran M, Karlsson Hedestam G, Garrett N, Abdool Karim S, Moore P, et al.
Immunogenetics
. 2024 Dec;
77(1):6.
PMID: 39627383
The heavy chain of an antibody is crucial for mediating antigen binding. IGHV genes, which partially encode the heavy chain of antibodies, exhibit vast genetic diversity largely through polymorphism and...
8.
Naicker N, Osman F, Naidoo K, Bodley N, Mbambo N, Madlala S, et al.
Sex Transm Infect
. 2024 Nov;
PMID: 39557497
Objectives: Human papillomavirus (HPV) can cause cervical cancer, a leading cause of female cancer mortality in South Africa and worldwide. We assessed the burden of, and factors associated with, HPV...
9.
Ismail S, Sebaa S, Abrahams B, Nason M, Mumby M, Dikeakos J, et al.
bioRxiv
. 2024 Nov;
PMID: 39554110
HIV-1 Nef mediates immune evasion and viral pathogenesis in part through downregulation of cell surface cluster of differentiation 4 (CD4) and major histocompatibility complex class I (MHC-I) on infected cells....
10.
Tlhaku K, Msimango L, Sookrajh Y, Milford C, Munatsi P, Gray A, et al.
PLOS Glob Public Health
. 2024 Aug;
4(8):e0003517.
PMID: 39121062
During the COVID-19 pandemic, the South African Centralized Chronic Medicines Dispensing and Distribution (CCMDD) programme, adapted to include extended 12-month antiretroviral therapy (ART) prescriptions, 3-months ART refills and earlier eligibility...