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Derrick Rancourt

Explore the profile of Derrick Rancourt including associated specialties, affiliations and a list of published articles. Areas
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Articles 14
Citations 109
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Recent Articles
1.
Lee I, Fegan J, Currie E, Bojagora A, Leung N, Rancourt D, et al.
bioRxiv . 2024 Sep; PMID: 39282262
is a human-restricted bacteria that is a normal nasopharyngeal resident, yet it can also disseminate, causing invasive meningococcal disease. Meningococci are highly adapted to life in humans, with human-specific virulence...
2.
Conrad J, Meyer S, Ramesh P, Neira J, Rusteika M, Mamott D, et al.
Stem Cell Reports . 2023 Nov; 18(12):2328-2343. PMID: 37949072
Sus scrofa domesticus (pig) has served as a superb large mammalian model for biomedical studies because of its comparable physiology and organ size to humans. The derivation of transgene-free porcine...
3.
Bourhill T, Rohani L, Kumar M, Bose P, Rancourt D, Johnston R
Viruses . 2023 Jul; 15(7). PMID: 37515162
Oncolytic viruses (OVs) are an emerging cancer therapeutic that are intended to act by selectively targeting and lysing cancerous cells and by stimulating anti-tumour immune responses, while leaving normal cells...
4.
Chu T, Baral K, Labit E, Rosin N, Sinha S, Umansky D, et al.
Glia . 2022 Jul; 70(11):2131-2156. PMID: 35796321
Skin is an easily accessible tissue and a rich source of Schwann cells (SCs). Toward potential clinical application of autologous SC therapies, we aim to improve the reliability and specificity...
5.
Sakib S, Voigt A, Martins Lara N, Su L, Ungrin M, Rancourt D, et al.
Int J Mol Sci . 2021 Dec; 22(24). PMID: 34948348
Male survivors of childhood cancer are at risk of suffering from infertility in adulthood because of gonadotoxic chemotherapies. For adult men, sperm collection and preservation are routine procedures prior to...
6.
Rohani L, Machiraju P, Sabouny R, Meng G, Liu S, Zhao T, et al.
Can J Cardiol . 2020 Feb; 36(4):554-563. PMID: 32046906
Background: Dilated cardiomyopathy with ataxia syndrome (DCMA) is an understudied autosomal recessive disease caused by loss-of-function mutations in the poorly characterized gene DNAJC19. Clinically, DCMA is commonly associated with heart...
7.
Lee P, Hess R, Friedrichs J, Haenchen V, Eckert H, Cuniberti G, et al.
J Tissue Eng Regen Med . 2019 Jun; 13(9):1672-1684. PMID: 31250556
Bone development and homeostasis are intricate processes that require co-existence and dynamic interactions among multiple cell types. However, controlled dynamic niches that derive and support stable propagation of these cells...
8.
Lee P, Eckert H, Hess R, Gelinsky M, Rancourt D, Krawetz R, et al.
Tissue Eng Part C Methods . 2017 Apr; 23(5):286-297. PMID: 28401793
Skeletal development is a multistep process that involves the complex interplay of multiple cell types at different stages of development. Besides biochemical and physical cues, oxygen tension also plays a...
9.
Sakib S, Dores C, Rancourt D, Dobrinski I
Methods Mol Biol . 2016 Apr; 1502:111-8. PMID: 27066790
Spermatogenesis is a stem cell based system. Both therapeutic and biomedical research applications of spermatogonial stem cells require a large number of cells. However, there are only few germ line...
10.
Alfred R, Radford J, Fan J, Boon K, Krawetz R, Rancourt D, et al.
Biotechnol Prog . 2011 May; 27(3):811-23. PMID: 21538971
Large numbers of cells will be required for successful embryonic stem cell (ESC)-based cellular therapies or drug discovery, thus raising the need to develop scaled-up bioprocesses for production of ESCs...