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Derick Hoskinson

Explore the profile of Derick Hoskinson including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Graber J, Hoskinson D, Liu H, Michaels K, Benson P, Maki N, et al.
Genetics . 2023 Nov; 226(2). PMID: 37967370
The Pcf11 protein is an essential subunit of the large complex that cleaves and polyadenylates eukaryotic mRNA precursor. It has also been functionally linked to gene-looping, termination of RNA Polymerase...
2.
Parikh K, Huether R, White K, Hoskinson D, Beaubier N, Dong H, et al.
JAMA Netw Open . 2020 Feb; 3(2):e200202. PMID: 32108894
Importance: Tumor mutation burden (TMB) is an emerging factor associated with survival with immunotherapy. When tumor-normal pairs are available, TMB is determined by calculating the difference between somatic and germline...
3.
Senol-Cosar O, Schmidt R, Qian E, Hoskinson D, Mason-Suares H, Funke B, et al.
Genet Med . 2019 Jun; 21(12):2765-2773. PMID: 31147632
Purpose: Clinically relevant variants exhibit a wide range of penetrance. Medical practice has traditionally focused on highly penetrant variants with large effect sizes and, consequently, classification and clinical reporting frameworks...
4.
Yang F, Hsu P, Lee S, Yang W, Hoskinson D, Xu W, et al.
RNA . 2016 Oct; 23(1):98-107. PMID: 27780845
3'-End processing of pre-mRNAs prior to packaging and export to the cytoplasm of the mature transcript is a highly regulated process executed by several tens of protein factors that recognize...
5.
Graber J, Nazeer F, Yeh P, Kuehner J, Borikar S, Hoskinson D, et al.
Genome Res . 2013 Jun; 23(10):1690-703. PMID: 23788651
Systemic response to DNA damage and other stresses is a complex process that includes changes in the regulation and activity of nearly all stages of gene expression. One gene regulatory...