Derek Walsh
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Explore the profile of Derek Walsh including associated specialties, affiliations and a list of published articles.
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53
Citations
1943
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Recent Articles
1.
Khalatyan N, Cornish D, Ferrell A, Savas J, Shen P, Hultquist J, et al.
Cell Rep
. 2025 Jan;
44(1):115119.
PMID: 39786991
Growing evidence suggests that ribosomes selectively regulate translation of specific mRNA subsets. Here, quantitative proteomics and cryoelectron microscopy demonstrate that poxvirus infection does not alter ribosomal subunit protein (RP) composition...
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Meade N, Toreev H, Chakrabarty R, Hesser C, Park C, Chandel N, et al.
Nat Commun
. 2023 Nov;
14(1):7889.
PMID: 38036506
Poxviruses are unusual DNA viruses that replicate in the cytoplasm. To do so, they encode approximately 100 immunomodulatory proteins that counteract cytosolic nucleic acid sensors such as cGAMP synthase (cGAS)...
4.
Hesser C, Walsh D
J Virol
. 2023 Mar;
97(3):e0175822.
PMID: 36916936
Recent studies have begun to reveal the complex and multifunctional roles of -methyladenosine (mA) modifications and their associated writer, reader, and eraser proteins in infection by diverse RNA and DNA...
5.
Goodrum F, Lowen A, Lakdawala S, Alwine J, Casadevall A, Imperiale M, et al.
mSphere
. 2023 Jan;
8(2):e0003423.
PMID: 36700653
Viruses have brought humanity many challenges: respiratory infection, cancer, neurological impairment and immunosuppression to name a few. Virology research over the last 60+ years has responded to reduce this disease...
6.
Goodrum F, Lowen A, Lakdawala S, Alwine J, Casadevall A, Imperiale M, et al.
mBio
. 2023 Jan;
14(1):e0018823.
PMID: 36700642
Viruses have brought humanity many challenges: respiratory infection, cancer, neurological impairment and immunosuppression to name a few. Virology research over the last 60+ years has responded to reduce this disease...
7.
Goodrum F, Lowen A, Lakdawala S, Alwine J, Casadevall A, Imperiale M, et al.
J Virol
. 2023 Jan;
97(2):e0008923.
PMID: 36700640
Viruses have brought humanity many challenges: respiratory infection, cancer, neurological impairment and immunosuppression to name a few. Virology research over the last 60+ years has responded to reduce this disease...
8.
Park C, Walsh D
Curr Opin Virol
. 2022 Oct;
56:101256.
PMID: 36270183
Poxviruses are large double-stranded DNA viruses that encode their own DNA replication, transcription, and mRNA biogenesis machinery, which underlies their ability to replicate entirely in the cytoplasm. However, like all...
9.
Park C, Walsh D
J Virol
. 2022 Sep;
96(18):e0109322.
PMID: 36098514
Receptor for activated C kinase 1 (RACK1) is a small ribosomal subunit protein that is phosphorylated by vaccinia virus (VacV) to maximize translation of postreplicative (PR) mRNAs that harbor 5'...
10.
Pegg C, Zaichick S, Bomba-Warczak E, Jovasevic V, Kim D, Kharkwal H, et al.
Nature
. 2021 Nov;
599(7886):662-666.
PMID: 34789877
Neurotropic alphaherpesviruses initiate infection in exposed mucosal tissues and, unlike most viruses, spread rapidly to sensory and autonomic nerves where life-long latency is established. Recurrent infections arise sporadically from the...