Derek Stemple
Overview
Explore the profile of Derek Stemple including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
13
Citations
714
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0
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Related Specialties
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Recent Articles
1.
Camargo-Sosa K, Colanesi S, Muller J, Schulte-Merker S, Stemple D, Patton E, et al.
PLoS Genet
. 2019 Feb;
15(2):e1007941.
PMID: 30811380
Skin pigment patterns are important, being under strong selection for multiple roles including camouflage and UV protection. Pigment cells underlying these patterns form from adult pigment stem cells (APSCs). In...
2.
Osborn D, Roccasecca R, McMurray F, Hernandez-Hernandez V, Mukherjee S, Barroso I, et al.
PLoS One
. 2014 Feb;
9(2):e87662.
PMID: 24503721
Common intronic variants in the Human fat mass and obesity-associated gene (FTO) are found to be associated with an increased risk of obesity. Overexpression of FTO correlates with increased food...
3.
Harvey S, Sealy I, Kettleborough R, Fenyes F, White R, Stemple D, et al.
Development
. 2013 May;
140(13):2703-10.
PMID: 23720042
Transcription is an essential component of basic cellular and developmental processes. However, early embryonic development occurs in the absence of transcription and instead relies upon maternal mRNAs and proteins deposited...
4.
Armant O, Marz M, Schmidt R, Ferg M, Diotel N, Ertzer R, et al.
Dev Biol
. 2013 May;
380(2):351-62.
PMID: 23684812
Transcription is the primary step in the retrieval of genetic information. A substantial proportion of the protein repertoire of each organism consists of transcriptional regulators (TRs). It is believed that...
5.
Cvejic A, Haer-Wigman L, Stephens J, Kostadima M, Smethurst P, Frontini M, et al.
Nat Genet
. 2013 Apr;
45(5):542-545.
PMID: 23563608
The blood group Vel was discovered 60 years ago, but the underlying gene is unknown. Individuals negative for the Vel antigen are rare and are required for the safe transfusion...
6.
Stevens E, Carss K, Cirak S, Foley A, Torelli S, Willer T, et al.
Am J Hum Genet
. 2013 Mar;
92(3):354-65.
PMID: 23453667
Mutations in several known or putative glycosyltransferases cause glycosylation defects in α-dystroglycan (α-DG), an integral component of the dystrophin glycoprotein complex. The hypoglycosylation reduces the ability of α-DG to bind...
7.
Otten C, van der Ven P, Lewrenz I, Paul S, Steinhagen A, Busch-Nentwich E, et al.
PLoS One
. 2012 Feb;
7(2):e31041.
PMID: 22355335
Myocellular regeneration in vertebrates involves the proliferation of activated progenitor or dedifferentiated myogenic cells that have the potential to replenish lost tissue. In comparison little is known about cellular repair...
8.
Gieger C, Radhakrishnan A, Cvejic A, Tang W, Porcu E, Pistis G, et al.
Nature
. 2011 Dec;
480(7376):201-8.
PMID: 22139419
Platelets are the second most abundant cell type in blood and are essential for maintaining haemostasis. Their count and volume are tightly controlled within narrow physiological ranges, but there is...
9.
Whiteley A, Bhat A, Martins E, Mayden R, Arunachalam M, Uusi-Heikkila S, et al.
Mol Ecol
. 2011 Sep;
20(20):4259-76.
PMID: 21923777
Understanding a wider range of genotype-phenotype associations can be achieved through ecological and evolutionary studies of traditional laboratory models. Here, we conducted the first large-scale geographic analysis of genetic variation...
10.
Zheng W, Wang Z, Collins J, Andrews R, Stemple D, Gong Z
PLoS One
. 2011 Sep;
6(8):e24019.
PMID: 21887364
The fish swimbladder is a unique organ in vertebrate evolution and it functions for regulating buoyancy in most teleost species. It has long been postulated as a homolog of the...