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Derek R Holman

Explore the profile of Derek R Holman including associated specialties, affiliations and a list of published articles. Areas
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Citations 100
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Recent Articles
1.
Holman D, Rubin S, Ferenc M, Holman E, Koron A, Daniel R, et al.
Sci Rep . 2024 Aug; 14(1):18934. PMID: 39147769
The utility of spatial omics in leveraging cellular interactions in normal and diseased states for precision medicine is hampered by a lack of strategies for matching disease states with spatial...
2.
Dharmaraj T, Kratochvil M, Pourtois J, Chen Q, Hajfathalian M, Hargil A, et al.
PNAS Nexus . 2023 Dec; 2(12):pgad406. PMID: 38111822
Extensive efforts are underway to develop bacteriophages as therapies against antibiotic-resistant bacteria. However, these efforts are confounded by the instability of phage preparations and a lack of suitable tools to...
3.
Dharmaraj T, Kratochvil M, Pourtois J, Chen Q, Hajfathalian M, Hargil A, et al.
bioRxiv . 2023 Jul; PMID: 37425882
Extensive efforts are underway to develop bacteriophages as therapies against antibiotic-resistant bacteria. However, these efforts are confounded by the instability of phage preparations and a lack of suitable tools to...
4.
Mayer A, Holman D, Sood A, Tandon U, Bhate S, Bodapati S, et al.
Sci Adv . 2023 Jan; 9(3):eadd1166. PMID: 36662860
Although literature suggests that resistance to TNF inhibitor (TNFi) therapy in patients with ulcerative colitis (UC) is partially linked to immune cell populations in the inflamed region, there is still...
5.
Gubatan J, Boye T, Temby M, Sojwal R, Holman D, Sinha S, et al.
Microorganisms . 2022 Jul; 10(7). PMID: 35889090
The gut microbiome has increasingly been recognized as a critical and central factor in inflammatory bowel disease (IBD). Here, we review specific microorganisms that have been suggested to play a...
6.
Stibbe J, Hoogland P, Achterberg F, Holman D, Sojwal R, Burggraaf J, et al.
Mol Imaging Biol . 2022 Jun; 25(1):18-35. PMID: 35764908
Flexible high-definition white-light endoscopy is the current gold standard in screening for cancer and its precursor lesions in the gastrointestinal tract. However, miss rates are high, especially in populations at...
7.
Gubatan J, Holman D, Puntasecca C, Polevoi D, Rubin S, Rogalla S
World J Gastroenterol . 2021 Dec; 27(43):7402-7422. PMID: 34887639
Antimicrobial peptides (AMP) are highly diverse and dynamic molecules that are expressed by specific intestinal epithelial cells, Paneth cells, as well as immune cells in the gastrointestinal (GI) tract. They...
8.
Cramer N, Korotcov A, Bosomtwi A, Xu X, Holman D, Whiting K, et al.
Exp Neurol . 2018 Oct; 311:293-304. PMID: 30321497
We sought to understand the mechanisms underlying cognitive deficits that are reported to affect non-native subjects following their prolonged stay and/or work at high altitude (HA). We found that mice...
9.
Grant A, Wilkinson T, Holman D, Martin M
Appl Spectrosc . 2005 Oct; 59(9):1182-7. PMID: 16197643
Analysis of fingerprints has predominantly focused on matching the pattern of ridges to a specific person as a form of identification. The present work focuses on identifying extrinsic materials that...