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Derek Oldridge

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Articles 12
Citations 1087
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Recent Articles
1.
Wang K, Coutifaris P, Brocks D, Wang G, Azar T, Solis S, et al.
Cancer Cell . 2024 Aug; 42(9):1582-1597.e10. PMID: 39214097
Combination checkpoint blockade with anti-PD-1 and anti-CTLA-4 antibodies has shown promising efficacy in melanoma. However, the underlying mechanism in humans remains unclear. Here, we perform paired single-cell RNA and T ...
2.
Bandyopadhyay S, Duffy M, Ahn K, Sussman J, Pang M, Smith D, et al.
Cell . 2024 May; 187(12):3120-3140.e29. PMID: 38714197
Non-hematopoietic cells are essential contributors to hematopoiesis. However, heterogeneity and spatial organization of these cells in human bone marrow remain largely uncharacterized. We used single-cell RNA sequencing (scRNA-seq) to profile...
3.
Bandyopadhyay S, Duffy M, Ahn K, Pang M, Smith D, Duncan G, et al.
bioRxiv . 2024 Apr; PMID: 38559168
The bone marrow is the organ responsible for blood production. Diverse non-hematopoietic cells contribute essentially to hematopoiesis. However, these cells and their spatial organization remain largely uncharacterized as they have...
4.
Asnani M, Hayer K, Naqvi A, Zheng S, Yang S, Oldridge D, et al.
Leukemia . 2019 Oct; 34(4):1202-1207. PMID: 31591467
No abstract available.
5.
Rajbhandari P, Lopez G, Capdevila C, Salvatori B, Yu J, Rodriguez-Barrueco R, et al.
Cancer Discov . 2018 Mar; 8(5):582-599. PMID: 29510988
High-risk neuroblastomas show a paucity of recurrent somatic mutations at diagnosis. As a result, the molecular basis for this aggressive phenotype remains elusive. Recent progress in regulatory network analysis helped...
6.
Deveau P, Colmet Daage L, Oldridge D, Bernard V, Bellini A, Chicard M, et al.
Bioinformatics . 2018 Jan; 34(11):1808-1816. PMID: 29342233
Motivation: In cancer, clonal evolution is assessed based on information coming from single nucleotide variants and copy number alterations. Nonetheless, existing methods often fail to accurately combine information from both...
7.
Zhu S, Zhang X, Weichert-Leahey N, Dong Z, Zhang C, Lopez G, et al.
Cancer Cell . 2017 Sep; 32(3):310-323.e5. PMID: 28867147
A genome-wide association study identified LMO1, which encodes an LIM-domain-only transcriptional cofactor, as a neuroblastoma susceptibility gene that functions as an oncogene in high-risk neuroblastoma. Here we show that dβh...
8.
Dubois S, Mody R, Naranjo A, Van Ryn C, Russ D, Oldridge D, et al.
Pediatr Blood Cancer . 2017 Apr; 64(11). PMID: 28383813
Background: Prior studies suggest that neuroblastomas that do not accumulate metaiodobenzylguanidine (MIBG) on diagnostic imaging (MIBG non-avid) may have more favorable features compared with MIBG avid tumors. We compared clinical...
9.
Zhou H, Vallieres M, Bai H, Su C, Tang H, Oldridge D, et al.
Neuro Oncol . 2017 Mar; 19(6):862-870. PMID: 28339588
Background: Previous studies have shown that MR imaging features can be used to predict survival and molecular profile of glioblastoma. However, no study of a similar type has been performed...
10.
Sotillo E, Barrett D, Black K, Bagashev A, Oldridge D, Wu G, et al.
Cancer Discov . 2015 Oct; 5(12):1282-95. PMID: 26516065
Unlabelled: The CD19 antigen, expressed on most B-cell acute lymphoblastic leukemias (B-ALL), can be targeted with chimeric antigen receptor-armed T cells (CART-19), but relapses with epitope loss occur in 10%...