Derek Macallan
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Explore the profile of Derek Macallan including associated specialties, affiliations and a list of published articles.
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23
Citations
858
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Recent Articles
11.
Costa Del Amo P, Lahoz-Beneytez J, Boelen L, Ahmed R, Miners K, Zhang Y, et al.
PLoS Biol
. 2018 Jun;
16(6):e2005523.
PMID: 29933397
Adaptive immunity relies on the generation and maintenance of memory T cells to provide protection against repeated antigen exposure. It has been hypothesised that a self-renewing population of T cells,...
12.
Patel A, Zhang Y, Fullerton J, Boelen L, Rongvaux A, Maini A, et al.
J Exp Med
. 2017 Jun;
214(7):1913-1923.
PMID: 28606987
In humans, the monocyte pool comprises three subsets (classical, intermediate, and nonclassical) that circulate in dynamic equilibrium. The kinetics underlying their generation, differentiation, and disappearance are critical to understanding both...
13.
Lahoz-Beneytez J, Schaller S, Macallan D, Eissing T, Niederalt C, Asquith B
Front Immunol
. 2017 May;
8:474.
PMID: 28487698
[6,6-H]-glucose labeling is a state-of-the-art technique for quantifying cell proliferation and cell disappearance in humans. However, there are discrepancies between estimates of T cell proliferation reported in short (1-day) versus...
14.
Arnold A, Witney A, Vergnano S, Roche A, Cosgrove C, Houston A, et al.
J Infect
. 2016 Jun;
73(3):210-8.
PMID: 27311749
Objectives: We describe the first published cluster of extensively drug resistant Tuberculosis (XDR-TB) in the UK and show how early whole genome sequencing (WGS) of Mtb can assist in case...
15.
Lahoz-Beneytez J, Elemans M, Zhang Y, Ahmed R, Salam A, Block M, et al.
Blood
. 2016 May;
127(26):3431-8.
PMID: 27136946
Human neutrophils have traditionally been thought to have a short half-life in blood; estimates vary from 4 to 18 hours. This dogma was recently challenged by stable isotope labeling studies...
16.
Zhang Y, de Lara C, Worth A, Hegedus A, Laamanen K, Beverley P, et al.
PLoS Pathog
. 2013 May;
9(4):e1003310.
PMID: 23637601
CD4(+) T-cell loss is the hallmark of HIV-1 infection. CD4 counts fall more rapidly in advanced disease when CCR5-tropic viral strains tend to be replaced by X4-tropic viruses. We hypothesized:...
17.
Wills M, Akbar A, Beswick M, Bosch J, Caruso C, Colonna-Romano G, et al.
Immun Ageing
. 2011 Nov;
8(1):10.
PMID: 22035114
The Second International Workshop on CMV & Immunosenescence was held in Cambridge, UK, 2-4th December, 2010. The presentations covered four separate sessions: cytomegalovirus and T cell phenotypes; T cell memory...
18.
Pawelec G, Akbar A, Beverley P, Caruso C, Derhovanessian E, Fulop T, et al.
Immun Ageing
. 2010 Sep;
7:13.
PMID: 20822513
No abstract available.
19.
Cresswell F, Eadie J, Longley N, Macallan D
Int J Infect Dis
. 2009 Jun;
14(2):e161-3.
PMID: 19502090
Varicella zoster virus (VZV) infection may trigger Guillain-Barré syndrome (GBS), but this is rare and almost always in the context of reactivation disease from latent VZV, 'shingles'. We report here...
20.
Lezin A, Olindo S, Belrose G, Signate A, Cesaire R, Smadja D, et al.
Front Biosci (Schol Ed)
. 2009 Jun;
1(1):205-15.
PMID: 19482696
HTLV-1 (human T-lymphotropic virus type 1) and BLV (bovine leukemia virus) are two related retroviruses infecting CD4+ and B lymphocytes in humans and ruminants, respectively. During infection, the host-pathogen interplay...