Derek J Sullivan
Overview
Explore the profile of Derek J Sullivan including associated specialties, affiliations and a list of published articles.
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45
Citations
1128
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Recent Articles
1.
OConnor-Moneley J, Fletcher J, Bean C, Parker J, Kelly S, Moran G, et al.
PLoS One
. 2024 Aug;
19(8):e0308665.
PMID: 39121069
Development of resistance and tolerance to antifungal drugs in Candida albicans can compromise treatment of infections caused by this pathogenic yeast species. The uniquely expanded C. albicans TLO gene family...
2.
Fletcher J, OConnor-Moneley J, Frawley D, Flanagan P, Alaalm L, Menendez-Manjon P, et al.
PLoS Genet
. 2023 Dec;
19(12):e1011082.
PMID: 38048294
The Candida albicans genome contains between ten and fifteen distinct TLO genes that all encode a Med2 subunit of Mediator. In order to investigate the biological role of Med2/Tlo in...
3.
OConnor-Moneley J, Alaalm L, Moran G, Sullivan D
Essays Biochem
. 2023 Apr;
67(5):843-851.
PMID: 37013399
Mediator is a complex of polypeptides that plays a central role in the recruitment of RNA polymerase II to promoters and subsequent transcriptional activation in eukaryotic organisms. Studies have now...
4.
Moran G, Anderson M, Myers L, Sullivan D
Curr Genet
. 2019 Jan;
65(3):621-630.
PMID: 30637479
Mediator complex has recently emerged as an important regulator of gene expression in pathogenic fungi. Mediator is a multi-subunit complex of polypeptides involved in transcriptional activation in eukaryotes, with roles...
5.
Flanagan P, Fletcher J, Boyle H, Sulea R, Moran G, Sullivan D
PLoS One
. 2018 Jul;
13(7):e0200852.
PMID: 30028853
The TLO genes are a family of subtelomeric ORFs in the fungal pathogens Candida albicans and C. dubliniensis encoding a subunit of the Mediator complex homologous to Med2. The more...
6.
Liu Z, Moran G, Sullivan D, MacCallum D, Myers L
PLoS Genet
. 2016 Oct;
12(10):e1006373.
PMID: 27741243
Filamentous growth is a hallmark of C. albicans pathogenicity compared to less-virulent ascomycetes. A multitude of transcription factors regulate filamentous growth in response to specific environmental cues. Our work, however,...
7.
Sullivan D, Berman J, Myers L, Moran G
PLoS Pathog
. 2015 Feb;
11(2):e1004614.
PMID: 25675446
No abstract available.
8.
Albaina O, Sahand I, Brusca M, Sullivan D, Fernandez de Larrinoa I, Moragues M
J Med Microbiol
. 2014 Dec;
64(Pt 2):147-156.
PMID: 25480879
Candida dubliniensis is a pathogenic yeast of the genus Candida closely related to Candida albicans. The phenotypic similarity of these two species often leads to misidentification of C. dubliniensis isolates...
9.
Haran J, Boyle H, Hokamp K, Yeomans T, Liu Z, Church M, et al.
PLoS Genet
. 2014 Oct;
10(10):e1004658.
PMID: 25356803
The TLO genes are a family of telomere-associated ORFs in the fungal pathogens Candida albicans and C. dubliniensis that encode a subunit of the Mediator complex with homology to Med2....
10.
Jordan R, Williams D, Moran G, Coleman D, Sullivan D
Med Mycol
. 2014 Mar;
52(3):254-63.
PMID: 24625677
Candida albicans and Candida dubliniensis are very closely related pathogenic yeast species. Despite their close relationship, C. albicans is a far more successful colonizer and pathogen of humans. The purpose...