Derek C Adams
Overview
Explore the profile of Derek C Adams including associated specialties, affiliations and a list of published articles.
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8
Citations
337
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Recent Articles
1.
Fetting J, Guay J, Karolak M, Iozzo R, Adams D, Maridas D, et al.
Development
. 2013 Nov;
141(1):17-27.
PMID: 24284212
Forkhead transcription factors are essential for diverse processes in early embryonic development and organogenesis. Foxd1 is required during kidney development and its inactivation results in failure of nephron progenitor cell...
2.
Brown A, Muthukrishnan S, Guay J, Adams D, Schafer D, Fetting J, et al.
Proc Natl Acad Sci U S A
. 2013 Mar;
110(12):4640-5.
PMID: 23487745
Embryonic nephron progenitor cells are segregated in molecularly distinct compartments of unknown function. Our study reveals an integral role for bone morphogenetic protein-SMAD in promoting transition of progenitors from the...
3.
Brown A, Blank U, Adams D, Karolak M, Fetting J, Hill B, et al.
J Vis Exp
. 2011 May;
(50).
PMID: 21540822
Embryonic development of the kidney has been extensively studied both as a model for epithelial-mesenchymal interaction in organogenesis and to gain understanding of the origins of congenital kidney disease. More...
4.
Adams D, Karolak M, Larman B, Liaw L, Nolin J, Oxburgh L
Am J Physiol Renal Physiol
. 2010 Sep;
299(6):F1320-7.
PMID: 20861081
Follistatin-like 1 (FSTL1) is a secreted protein with homology to both Follistatin and the SPARC/BM40 family of matricellular proteins. In this study, we sought to determine the expression patterns of...
5.
Blank U, Brown A, Adams D, Karolak M, Oxburgh L
Development
. 2009 Oct;
136(21):3557-66.
PMID: 19793891
The iterative formation of nephrons during embryonic development relies on continual replenishment of progenitor cells throughout nephrogenesis. Defining molecular mechanisms that maintain and regulate this progenitor pool is essential to...
6.
Adams D, Oxburgh L
Am J Physiol Renal Physiol
. 2009 Jun;
297(3):F809-15.
PMID: 19535568
Long-term pulse chase experiments previously identified a sizable population of BrdU-retaining cells within the renal papilla. The origin of these cells has been unclear, and in this work we test...
7.
Larman B, Karolak M, Adams D, Oxburgh L
J Am Soc Nephrol
. 2009 Apr;
20(5):1020-31.
PMID: 19357253
Stimulation of the bone morphogenetic protein (BMP) pathway protects the kidney from acute and chronic injury. Numerous regulators in the kidney control BMP signaling, offering many targets for therapeutic manipulation....
8.
Blank U, Seto M, Adams D, Wojchowski D, Karolak M, Oxburgh L
BMC Dev Biol
. 2008 Sep;
8:86.
PMID: 18801194
Background: Bone morphogenetic proteins (BMPs) regulate essential processes during organogenesis, and a functional understanding of these secreted proteins depends on identification of their target cells. In this study, we generate...