Dennis Eickelbeck
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Explore the profile of Dennis Eickelbeck including associated specialties, affiliations and a list of published articles.
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7
Citations
81
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Recent Articles
1.
Barzan R, Bozkurt B, Nejad M, Suss S, Surdin T, Boke H, et al.
Nat Commun
. 2024 Sep;
15(1):8078.
PMID: 39277631
Response gain is a crucial means by which modulatory systems control the impact of sensory input. In the visual cortex, the serotonergic 5-HT receptor is key in such modulation. However,...
2.
Karapinar R, Schwitalla J, Eickelbeck D, Pakusch J, Mucher B, Grommke M, et al.
Nat Commun
. 2021 Jul;
12(1):4488.
PMID: 34301944
Opn7b is a non-visual G protein-coupled receptor expressed in zebrafish. Here we find that Opn7b expressed in HEK cells constitutively activates the G pathway and illumination with blue/green light inactivates...
3.
Eickelbeck D, Rudack T, Tennigkeit S, Surdin T, Karapinar R, Schwitalla J, et al.
Chembiochem
. 2019 Aug;
21(5):612-617.
PMID: 31468691
Optogenetics uses light-sensitive proteins, so-called optogenetic tools, for highly precise spatiotemporal control of cellular states and signals. The major limitations of such tools include the overlap of excitation spectra, phototoxicity,...
4.
Tennigkeit S, Karapinar R, Rudack T, Dreier M, Althoff P, Eickelbeck D, et al.
Chembiochem
. 2019 Mar;
20(14):1766-1771.
PMID: 30920724
The primary goal of optogenetics is the light-controlled noninvasive and specific manipulation of various cellular processes. Herein, we present a hybrid strategy for targeted protein engineering combining computational techniques with...
5.
Eickelbeck D, Karapinar R, Jack A, Suess S, Barzan R, Azimi Z, et al.
Commun Biol
. 2019 Feb;
2:60.
PMID: 30793039
The signal specificity of G protein-coupled receptors (GPCRs) including serotonin receptors (5-HT-R) depends on the trafficking and localization of the GPCR within its subcellular signaling domain. Visualizing traffic-dependent GPCR signals...
6.
Mark M, Donner M, Eickelbeck D, Stepien J, Nowrousian M, Kuck U, et al.
PLoS One
. 2018 Jul;
13(7):e0198765.
PMID: 29995896
Bioluminescence is a fascinating phenomenon and can be found in many different organisms including fish. It has been suggested that bioluminescence is used for example for defense, prey attraction, and...
7.
Spoida K, Eickelbeck D, Karapinar R, Eckhardt T, Mark M, Jancke D, et al.
Curr Biol
. 2016 Apr;
26(9):1206-12.
PMID: 27068418
G-protein-coupled receptors (GPCRs) represent the major protein family for cellular modulation in mammals. Therefore, various strategies have been developed to analyze the function of GPCRs involving pharmaco- and optogenetic approaches...