Dennis Chan
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Explore the profile of Dennis Chan including associated specialties, affiliations and a list of published articles.
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60
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1622
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Recent Articles
1.
Patel A, Gilpin G, Koniotes A, Warren C, Xu C, Burgess P, et al.
Brain Behav Immun Health
. 2024 Dec;
43:100917.
PMID: 39717873
Background: Cognitive impairment, colloquially termed "brain fog", is one of the most prevalent manifestations of post-Covid syndrome and a major contributor to impaired daily function and reduced quality of life....
2.
Rowland H, Miller G, Liu Q, Li S, Sharp N, Ng B, et al.
Stem Cells
. 2024 Dec;
43(3).
PMID: 39704342
Human induced pluripotent stem cells (iPSCs) provide powerful cellular models of Alzheimer's disease (AD) and offer many advantages over non-human models, including the potential to reflect variation in individual-specific pathophysiology...
3.
Vanova M, Patel A, Scott I, Gilpin G, Manning E, Ash C, et al.
Trials
. 2024 Oct;
25(1):704.
PMID: 39434179
Background: Between 25 and 75% of people with persistent post-acute sequelae of SARS-CoV-2 infection (PASC) experience cognitive difficulties, compromising functional ability, quality of life, and activities of daily living, including...
4.
McConnell E, Chan D, Ventura K, Callahan J, Harris K, Hunt V, et al.
Mol Ther Nucleic Acids
. 2024 Oct;
35(3):102251.
PMID: 39377064
A neuropathological hallmark of Parkinson's disease (PD) is the aggregation and spreading of misfolded α-synuclein (αSyn) protein. In this study, a selection method was developed to identify aptamers that showed...
5.
Foret-Bruno P, Shafran R, Stephenson T, Nugawela M, Chan D, Ladhani S, et al.
Brain Behav Immun
. 2024 May;
119:989-994.
PMID: 38735404
Background: Cognitive impairment is often reported after SARS-CoV-2 infection, yet evidence gaps remain. We aimed to (i) report the prevalence and characteristics of children and young people (CYP) reporting "brain...
6.
cepukaityte G, Newton C, Chan D
Alzheimers Dement
. 2024 Mar;
20(4):3054-3073.
PMID: 38425234
Wearable digital technologies capable of measuring everyday behaviors could improve the early detection of dementia-causing diseases. We conducted two systematic reviews following Preferred Reporting Items for Systematic reviews and Meta-Analyses...
7.
Newton C, Pope M, Rua C, Henson R, Ji Z, Burgess N, et al.
Alzheimers Dement
. 2024 Feb;
20(4):2779-2793.
PMID: 38421123
Introduction: Entorhinal cortex (EC) is the first cortical region to exhibit neurodegeneration in Alzheimer's disease (AD), associated with EC grid cell dysfunction. Given the role of grid cells in path...
8.
Ross D, Chan D, Kuo E, Harkenrider M
Pract Radiat Oncol
. 2024 Feb;
14(3):234-240.
PMID: 38387781
Purpose: Non-small cell lung cancer (NSCLC) local control remains suboptimal with rates around 75%. Stereotactic body radiation therapy (SBRT) is an option for isolated local recurrences of small-volume recurrences. This...
9.
Castegnaro A, Ji Z, Rudzka K, Chan D, Burgess N
Curr Biol
. 2023 Oct;
33(21):4650-4661.e7.
PMID: 37827151
Path integration (PI) is impaired early in Alzheimer's disease (AD) but reflects multiple sub-processes that may be differentially sensitive to AD. To characterize these sub-processes, we developed a novel generative...
10.
Massey R, McConnell E, Chan D, Holahan M, DeRosa M, Prakash R
ACS Sens
. 2023 Jul;
8(8):3116-3126.
PMID: 37506391
Parkinson's disease (PD) currently affects more than 1 million people in the US alone, with nearly 8.5 million suffering from the disease worldwide, as per the World Health Organization. However,...