Deniz Cansen Kahraman
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Explore the profile of Deniz Cansen Kahraman including associated specialties, affiliations and a list of published articles.
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18
Citations
153
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Recent Articles
1.
Binarci B, Kilic E, Dogan T, Cetin Atalay R, Kahraman D, Nacak Baytas S
Drug Dev Res
. 2024 Oct;
85(7):e70008.
PMID: 39428864
Hepatocellular carcinoma (HCC) is a leading cause of cancer-related mortality worldwide, driven mainly by chronic hepatitis infections and metabolic disorders, which highlights the urgent need for novel therapeutic strategies. Sirtuins,...
2.
Hawash M, Guntekin Ergun S, Kahraman D, Olgac A, Hamel E, Cetin-Atalay R, et al.
J Mol Struct
. 2023 May;
1285.
PMID: 37234266
Structurally diverse indole-3-pyrazole-5-carboxamide analogues () were designed, synthesized, and evaluated for their antiproliferative activity against three cancer cell lines (Huh7, MCF-7, and HCT116) using the sulforhodamine B assay. Some of...
3.
Hawash M, Jaradat N, Abualhasan M, Sukuroglu M, Qaoud M, Kahraman D, et al.
BMC Chem
. 2023 Mar;
17(1):11.
PMID: 36879343
Background: Nonsteroidal anti-inflammatory drugs (NSAIDs) have been the most commonly used class of medications worldwide for the last three decades. Objectives: This study aimed to design and synthesize a novel...
4.
Kahraman D, Bilget Guven E, Aytac P, Aykut G, Tozkoparan B, Cetin Atalay R
Sci Rep
. 2022 Sep;
12(1):15139.
PMID: 36071119
Hepatocellular carcinoma (HCC) is a highly heterogeneous cancer, and resistant to both conventional and targeted chemotherapy. Recently, nonsteroidal anti-inflammatory drugs (NSAIDs) have been shown to decrease the incidence and mortality...
5.
Narci K, Kahraman D, Koyas A, Ersahin T, Tuncbag N, Cetin Atalay R
BMC Cancer
. 2022 Mar;
22(1):320.
PMID: 35331184
Background: Targeted therapies for Primary liver cancer (HCC) is limited to the multi-kinase inhibitors, and not fully effective due to the resistance to these agents because of the heterogeneous molecular...
6.
Surucu Yilmaz N, Bilgic Eltan S, Kayaoglu B, Geckin B, Heredia R, Sefer A, et al.
J Clin Immunol
. 2022 Jan;
42(3):582-596.
PMID: 35028801
NF-κB essential modulator (NEMO, IKK-γ) deficiency is a rare combined immunodeficiency caused by mutations in the IKBKG gene. Conventionally, patients are afflicted with life threatening recurrent microbial infections. Paradoxically, the...
7.
Hawash M, Kahraman D, Guntekin Ergun S, Cetin-Atalay R, Nacak Baytas S
BMC Chem
. 2021 Dec;
15(1):66.
PMID: 34930409
Background: Liver cancer is predicted to be the sixth most diagnosed cancer globally and fourth leading cause of cancer deaths. In this study, a series of indole-3-isoxazole-5-carboxamide derivatives were designed,...
8.
Cetin-Atalay R, Kahraman D, Nalbat E, Rifaioglu A, Atakan A, Donmez A, et al.
J Gastrointest Cancer
. 2021 Dec;
52(4):1266-1276.
PMID: 34910274
Purpose: Computational approaches have been used at different stages of drug development with the purpose of decreasing the time and cost of conventional experimental procedures. Lately, techniques mainly developed and...
9.
Ibis K, Nalbat E, Caliskan B, Kahraman D, Cetin-Atalay R, Banoglu E
Eur J Med Chem
. 2021 May;
221:113489.
PMID: 33951549
In our effort for the development of novel anticancer therapeutics, a series of isoxazole-piperazine analogues were prepared, and primarily screened for their antiproliferative potential against hepatocellular carcinoma (HCC; Huh7/Mahlavu) and...
10.
Gozen D, Kahraman D, Narci K, Shehwana H, Konu O, Cetin-Atalay R
Turk J Biol
. 2021 Apr;
45(2):149-161.
PMID: 33907497
Hepatocellular carcinoma (HCC) is one of the most common cancer types with high mortality rates and displays increased resistance to various stress conditions such as oxidative stress. Conventional therapies have...