Denisa Margina
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Explore the profile of Denisa Margina including associated specialties, affiliations and a list of published articles.
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52
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1353
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Recent Articles
11.
Celebi D, Taghizadehghalehjoughi A, Baser S, Genc S, Yilmaz A, Yeni Y, et al.
Mol Med Rep
. 2022 Aug;
26(3).
PMID: 35920188
Methicillin‑resistant (MRSA) infections are usually found in hospital settings and, frequently, in patients with open wounds. One of the most critical virulence factors affecting the severity and recurrence of infections...
12.
Ungurianu A, Zanfirescu A, Margina D
Plants (Basel)
. 2022 Jul;
11(13).
PMID: 35807694
The sirtuin family comprises NAD-dependent protein lysine deacylases, mammalian sirtuins being either nuclear (SIRT1, SIRT2, SIRT6, and SIRT7), mitochondrial (SIRT3, SIRT4, and SIRT5) or cytosolic enzymes (SIRT2 and SIRT5). They...
13.
Ungurianu A, Zanfirescu A, Gradinaru D, Ionescu-Tirgoviste C, Danciulescu Miulescu R, Margina D
Curr Med Res Opin
. 2022 Jan;
38(4):511-522.
PMID: 35067142
Background: Type 2 diabetes mellitus (T2DM) represents a leading cause of morbidity and premature mortality, low-grade inflammation being acknowledged as a key contributor to its development and progression. A tailored...
14.
Purdel C, Ungurianu A, Margina D
Front Mol Biosci
. 2021 Dec;
8:783065.
PMID: 34926582
Type 1 diabetes mellitus (T1DM) is currently considered an autoimmune disease characterized by the destruction of pancreatic β-cells, insulin deficiency, and dysglycemia. Dietary factors, including omega-3 polyunsaturated fatty acids (ω-3...
15.
Volynets G, Vyshniakova H, Nitulescu G, Nitulescu G, Ungurianu A, Margina D, et al.
Molecules
. 2021 Dec;
26(23).
PMID: 34885677
() is a causative agent of many hospital- and community-acquired infections with the tendency to develop resistance to all known antibiotics. Therefore, the development of novel antistaphylococcal agents is of...
16.
Gradinaru D, Margina D, Ungurianu A, Nitulescu G, Pena C, Ionescu-Tirgoviste C, et al.
Exp Ther Med
. 2021 Oct;
22(6):1393.
PMID: 34650641
Zinc deficiencies have been reported in numerous pathologies, such as diabetes mellitus, but also in the physiological process of ageing. Similarly, the end products of glycoxidation processes, advanced glycation end...
17.
Sevim C, Ozkaraca M, Kara M, Ulas N, Mendil A, Margina D, et al.
Environ Toxicol Pharmacol
. 2021 Aug;
87:103735.
PMID: 34461274
3-chloropropane-1,2-diol (3-MCPD) and its toxic metabolite glycidol were classified by the International Agency for Research on Cancer (IARC) as belonging to group 2B and 2A for humans. This study aimed...
18.
Gradinaru D, Ungurianu A, Margina D, Moreno-Villanueva M, Burkle A
Oxid Med Cell Longev
. 2021 Aug;
2021:3617042.
PMID: 34373764
Since its discovery in 1905 and its employment in everyday medical practice as a local anesthetic, to its highly controversial endorsement as an "anti-aging" molecule in the sixties and seventies,...
19.
Nitulescu G, Margina D, Zanfirescu A, Olaru O, Nitulescu G
Pharmaceuticals (Basel)
. 2021 May;
14(5).
PMID: 33946434
Increasingly ineffective antibiotics and rapid spread of multi- and pan-resistant bacteria represent a global health threat; hence, the need of developing new antimicrobial medicines. A first step in this direction...
20.
Ungurianu A, Zanfirescu A, Nitulescu G, Margina D
Antioxidants (Basel)
. 2021 Apr;
10(5).
PMID: 33919211
Vitamin E, comprising tocopherols and tocotrienols, is mainly known as an antioxidant. The aim of this review is to summarize the molecular mechanisms and signaling pathways linked to inflammation and...