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Anca Zanfirescu

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Articles 31
Citations 317
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Recent Articles
1.
Andrei C, Zanfirescu A, Ormeneanu V, Negres S
Antibiotics (Basel) . 2025 Feb; 14(2). PMID: 40001382
Background/objectives: Drug-induced dysbiosis, particularly from antibiotics, has emerged as a significant contributor to chronic diseases by disrupting gut microbiota composition and function. Plant-derived secondary metabolites, such as polysaccharides, polyphenols, alkaloids,...
2.
Puscasu C, Andrei C, Olaru O, Zanfirescu A
Curr Issues Mol Biol . 2025 Jan; 47(1). PMID: 39852178
Chronic pain is a debilitating condition affecting millions worldwide, often resulting from complex interactions between the nervous and immune systems. Recent advances highlight the critical role of metabolite-sensing G protein-coupled...
3.
Andrei C, Mihai D, Nitulescu G, Nitulescu G, Zanfirescu A
Int J Mol Sci . 2025 Jan; 25(24. PMID: 39769455
Osteoarthritis (OA) is a degenerative joint disease characterized by the breakdown of cartilage and the subsequent inflammation of joint tissues, leading to pain and reduced mobility. Despite advancements in symptomatic...
4.
Andrei C, Nitulescu G, Nitulescu G, Zanfirescu A
Pharmacy (Basel) . 2024 Dec; 12(6). PMID: 39728841
In recent years, the European market, including Romania, has witnessed a significant increase in the promotion of cannabidiol (CBD)-based products, often presented as effective treatments for various health conditions. This...
5.
Ungurianu A, Margina D, Mihai D, Nicolae A, Dragoi C, Gradinaru D, et al.
Adv Med Sci . 2024 Dec; 70(1):44-50. PMID: 39617052
Purpose: Caloric restriction (CR), the permanent or periodic reduction of caloric intake, is a dietary strategy that promotes longevity and healthspan, yielding multiple beneficial effects, such as improved insulin sensitivity...
6.
Ungurianu A, Zanfirescu A, Margina D
Phytother Res . 2024 Mar; 38(5):2361-2387. PMID: 38429891
As the global population ages, preventing lifestyle- and aging-related diseases is increasing, necessitating the search for safe and affordable therapeutic interventions. Among nutraceuticals, quercetin, a flavonoid ubiquitously present in various...
7.
Zanfirescu A, Avram I, Gatea F, Rosca R, Vamanu E
Life (Basel) . 2024 Jan; 14(1). PMID: 38255683
The increasing incidence of diabetes has prompted the need for new treatment strategies, including natural products that reduce glycemia values. This work examined the in vitro and in vivo antihyperglycemic...
8.
Puscasu C, Zanfirescu A, Negres S, Seremet O
Medicina (Kaunas) . 2023 Dec; 59(12). PMID: 38138293
Phosphodiesterase type 5 (PDE5) is pivotal in cellular signalling, regulating cyclic guanosine monophosphate (cGMP) levels crucial for smooth muscle relaxation and vasodilation. By targeting cGMP for degradation, PDE5 inhibits sustained...
9.
Andrei C, Mihai D, Nitulescu G, Ungurianu A, Margina D, Nitulescu G, et al.
Pharmaceuticals (Basel) . 2023 Nov; 16(11). PMID: 38004429
Osteoarthritis is characterized by progressive articular cartilage degradation, subchondral bone changes, and synovial inflammation, and affects various joints, causing pain and disability. Current osteoarthritis therapies, primarily focused on pain management,...
10.
Avram I, Pelinescu D, Gatea F, Ionescu R, Barcan A, Rosca R, et al.
Life (Basel) . 2023 Jul; 13(7). PMID: 37511858
The regular administration of antibiotics is a public concern due to the prejudices of large population groups and the high frequency with which antimicrobial products are prescribed. The current study...