Dengke Pan
Overview
Explore the profile of Dengke Pan including associated specialties, affiliations and a list of published articles.
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Articles
43
Citations
385
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Recent Articles
1.
Zhang M, Feng H, Huang Y, Hu T, Du J, Wang Y, et al.
Xenotransplantation
. 2025 Feb;
32(1):e70029.
PMID: 39994946
Background: CD40-CD154 pathway inhibitors are considered indispensable immunosuppressive drugs in xenotransplantation. At present, novel anti-CD154 and anti-CD40 monoclonal antibodies (mAbs) are continuously being developed. It is important to establish a...
2.
Feng H, Zhang M, Xia Q, Du J, Li T, Chen S, et al.
Xenotransplantation
. 2025 Feb;
32(1):e70021.
PMID: 39960350
Background: Gene-edited pigs for xenotransplantation usually contain one or more transgenes encoding human complement regulatory proteins (CRPs). Because of species differences, human CRP(s) expressed in gene-edited pigs may have difficulty...
3.
Huai G, Wang Y, Du J, Cheng Z, Xie Y, Zhou J, et al.
Front Immunol
. 2025 Feb;
15:1488552.
PMID: 39902050
Introduction: Genetically edited pigs, modified using CRISPR-Cas9 technology, hold promise as potential sources for xenotransplantation. However, the optimal combination of genetic modifications and their expression levels for initial clinical trials...
4.
Feng H, Zhang M, Xia Q, Du J, Li T, Chen S, et al.
Xenotransplantation
. 2025 Jan;
32(1):e70012.
PMID: 39825616
Background: Gene-edited pigs for xenotransplantation usually contain one or more transgenes encoding human complement regulatory proteins (CRPs). Because of species differences, human CRP(s) expressed in gene-edited pigs may have difficulty...
5.
Ma S, Qi R, Han S, Li Z, Zhang X, Wang G, et al.
Chin Med J (Engl)
. 2024 Oct;
PMID: 39420636
Background: The primary limitation to kidney transplantation is organ shortage. Recent progress in gene editing and immunosuppressive regimens has made xenotransplantation with porcine organs a possibility. However, evidence in pig-to-human...
6.
Wang Y, Chen G, Pan D, Guo H, Jiang H, Wang J, et al.
Cell Rep Med
. 2024 Sep;
5(10):101744.
PMID: 39317190
This study develops an observational model to assess kidney function recovery and xenogeneic immune responses in kidney xenotransplants, focusing on gene editing and immunosuppression. Two brain-dead patients undergo single kidney...
7.
Zhang M, Feng H, Du J, Chen S, Zhu L, Wang Y, et al.
Xenotransplantation
. 2024 Jul;
31(4):e12876.
PMID: 39031102
Background: Long-term immunosuppressive maintenance therapy is necessary to prevent the rejection of xenografts. However, it is still unclear which oral immunosuppressant is most suitable for pig-to-human xenotransplantation . Methods: A...
8.
Zhang A, Lu L, Yang F, Luo T, Yang S, Yang P, et al.
Adipocyte
. 2024 Jun;
13(1):2365211.
PMID: 38858810
microRNAs (miRNAs), a subclass of noncoding short RNAs, direct cells fate decisions that are important for cell proliferation and cell lineage decisions. Adipogenic differentiation contributes greatly to the development of...
9.
Huai G, Schuurman H, Cooper D, Buhler L, Deng S, Pan D
Xenotransplantation
. 2023 Oct;
30(6):e12829.
PMID: 37793086
A conference on progress in the development of xenotransplantation in China was held in Neijiang, Sichuan, in May 2023, and was attended by approximately 100 established researchers and trainees. Progress...
10.
Liu H, Pan D, Li P, Wang D, Xia B, Zhang R, et al.
Adv Sci (Weinh)
. 2023 Aug;
10(29):e2302298.
PMID: 37551034
Sepsis-induced muscle atrophy often increases morbidity and mortality in intensive care unit (ICU) patients, yet neither therapeutic target nor optimal animal model is available for this disease. Here, by modifying...