Denan Jin
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Explore the profile of Denan Jin including associated specialties, affiliations and a list of published articles.
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121
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1495
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Recent Articles
11.
Takai S, Jin D
Biomedicines
. 2022 Oct;
10(10).
PMID: 36289761
Chymase present in mast cells can directly form matrix metalloproteinase (MMP)-9 from proMMP-9. Chymase-activated MMP-9 has been reportedly closely related to the pathogenesis of various diseases, and inflammation-related diseases in...
12.
Yoneyama H, Hosohata K, Jin D, Yoshida I, Toyoda M, Kitamura I, et al.
Bioorg Med Chem
. 2022 May;
65:116791.
PMID: 35537325
Fourteen novel vanin-1 inhibitors coded OMP-# were designed from RR6 and successfully synthesized by a nucleophilic addition-elimination reaction of the pantetheinic acid-derived Weinreb amide as a key step under Barbier...
13.
Fujita Y, Jin D, Mimura M, Sato Y, Takai S, Kida T
Int J Mol Sci
. 2022 Mar;
23(5).
PMID: 35269701
The purpose of this present study was to investigate the distribution and expression of chymase in the lacrimal glands (LGs) of patients afflicted with IgG4-related ophthalmic disease (IgG4-ROD). LGs from...
14.
Yoshizaki Y, Nagata T, Fujiwara S, Takai S, Jin D, Kuzuya A, et al.
ACS Appl Bio Mater
. 2022 Jan;
4(4):3079-3088.
PMID: 35014396
Postoperative adhesion remains a problem in surgery and causes postoperative complications. Laparoscopic surgery is now common, making it increasingly important to develop injectable formulations of adhesion barriers that can be...
15.
Hosohata K, Jin D, Takai S
Int J Mol Sci
. 2022 Jan;
23(1).
PMID: 35008870
Ischemia-reperfusion injury is one of the major causes of acute kidney injury (AKI), which is increasingly prevalent in clinical settings. Glaucocalxin A (GLA), a biologically ent-kauranoid diterpenoid, has various pharmacological...
16.
Kinoshita I, Jin D, Higashino M, Terada T, Kurisu Y, Takai S, et al.
Int J Mol Sci
. 2021 Dec;
22(23).
PMID: 34884420
Incomplete excision of pleomorphic adenoma (PA) may result in recurrent pleomorphic adenoma (RPA). Furthermore, long-term neglected PA may become carcinoma ex pleomorphic adenoma (CXPA). In the present study, the relationships...
17.
Kuramoto T, Jin D, Komeda K, Taniguchi K, Hirokawa F, Takai S, et al.
Int J Mol Sci
. 2021 Nov;
22(22).
PMID: 34830195
Acute pancreatitis is still a life-threatening disease without an evidenced therapeutic agent. In this study, the effect of chymase in acute pancreatitis and the possible effect of a chymase inhibitor...
18.
Hosohata K, Jin D, Takai S
Int J Mol Sci
. 2021 Nov;
22(21).
PMID: 34768879
Oxidative stress plays an important role in the pathophysiology of acute kidney injury (AKI). Previously, we reported that vanin-1, which is involved in oxidative stress, is associated with renal tubular...
19.
Ikeda T, Nakamura K, Morishita S, Sato T, Horie T, Kida T, et al.
Ophthalmic Res
. 2021 Sep;
64(6):1002-1012.
PMID: 34515200
Introduction: We previously reported that the intravitreal activities of chymase and tryptase were more increased in the patients with macular hole (MH) and epiretinal membrane (ERM) than in those with...
20.
Morishita S, Sato T, Oosuka S, Horie T, Kida T, Oku H, et al.
Int J Mol Sci
. 2021 Mar;
22(4).
PMID: 33669860
We previously reported that the bursa premacularis (BPM), a peculiar vitreous structure located above the macula, contains numerous cells expressing markers of lymphatic endothelial cells, such as podoplanin and LYVE-1....