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Deepesh Pandey

Explore the profile of Deepesh Pandey including associated specialties, affiliations and a list of published articles. Areas
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Articles 24
Citations 702
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Recent Articles
1.
Ihrig C, Montgomery M, Nomura Y, Nakano M, Pandey D, La Favor J
Sex Med . 2025 Jan; 12(6):qfae096. PMID: 39790566
Background: Erectile dysfunction is a condition with a rapidly increasing prevalence globally with a strong correlation to the increase in obesity and cardiovascular disease rates. Aim: The aim of the...
2.
Jin Q, Pandey D, Thompson C, Lewis S, Sung H, Nguyen T, et al.
Biophys J . 2023 May; 122(18):3690-3703. PMID: 37254483
Fetal lung fibroblasts contribute dynamic infrastructure for the developing lung. These cells undergo dynamic mechanical transitions, including cyclic stretch and spreading, which are integral to lung growth in utero. We...
3.
Nomura Y, Nakano M, Sung H, Han M, Pandey D
Front Physiol . 2021 Jul; 12:675724. PMID: 34220539
We previously reported that histone deacetylase 6 (HDAC6) has an important role in endothelial cell (EC) function . However, whether HDAC6 plays a role in atherogenesis and the mechanism(s) that...
4.
Han M, Pandey D
Am J Respir Cell Mol Biol . 2021 May; 65(3):300-308. PMID: 34003736
Endothelial dysfunction is implicated in the thrombotic events reported in patients with coronavirus disease (COVID-19), but the underlying molecular mechanisms are unknown. Circulating levels of the coagulation cascade activator PAI-1...
5.
Hori D, Nomura Y, Nakano M, Han M, Bhatta A, Chen K, et al.
Cell Physiol Biochem . 2020 Sep; 54(5):947-958. PMID: 32975918
Background/aims: We recently described a novel regulatory role for histone deacetylase 2 (HDAC2) in protecting endothelial cells from oxidized low-density lipoprotein (OxLDL)-induced injury. In this study, we examined the effects...
6.
Chi Z, Byeon H, Seo E, Nguyen Q, Lee W, Jeong Y, et al.
Pharmacol Res . 2019 May; 146:104281. PMID: 31125601
Cystathionine γ-lyase (CSEγ) is a hydrogen sulfide (HS)-producing enzyme. Endothelial HS production can mediate vasodilatory effects, contributing to the alleviation of hypertension (high blood pressure). Recent studies have suggested a...
7.
Pandey D, Nomura Y, Rossberg M, Hori D, Bhatta A, Keceli G, et al.
Arterioscler Thromb Vasc Biol . 2018 Feb; 38(4):913-926. PMID: 29472234
Objective: KLF15 (Kruppel-like factor 15) has recently been shown to suppress activation of proinflammatory processes that contribute to atherogenesis in vascular smooth muscle, however, the role of KLF15 in vascular...
8.
Barreto Ortiz S, Hori D, Nomura Y, Yun X, Jiang H, Yong H, et al.
Am J Physiol Lung Cell Mol Physiol . 2017 Sep; 314(1):L93-L106. PMID: 28882814
We recently demonstrated that blue light induces vasorelaxation in the systemic mouse circulation, a phenomenon mediated by the nonvisual G protein-coupled receptor melanopsin (Opsin 4; Opn4). Here we tested the...
9.
Leucker T, Nomura Y, Kim J, Bhatta A, Wang V, Wecker A, et al.
Am J Physiol Heart Circ Physiol . 2017 Feb; 312(4):H711-H720. PMID: 28188215
Endothelial cystathionine γ-lyase (CSEγ) contributes to cardiovascular homeostasis, mainly through production of HS. However, the molecular mechanisms that control CSEγ gene expression in the endothelium during cardiovascular diseases are unclear....
10.
Carrillo-Sepulveda M, Spitler K, Pandey D, Berkowitz D, Matsumoto T
J Mol Med (Berl) . 2015 Jul; 93(12):1341-54. PMID: 26184970
Unlabelled: Hyperglycemia-induced reactive oxygen species (ROS) production plays a major role in the pathogenesis of diabetic vascular dysfunction. However, the underlying mechanisms remain unclear. Toll-like receptor 4 (TLR4), a key...