Deepak T Patel
Overview
Explore the profile of Deepak T Patel including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
2
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Recent Articles
1.
Patel D, Karimullina E, Guo Y, Semper C, Patel D, Emde T, et al.
Protein Sci
. 2025 Jan;
34(2):e70037.
PMID: 39865303
Polymyxins are last-resort antimicrobial peptides administered clinically against multi-drug resistant bacteria, specifically in the case of Gram-negative species. However, an increasing number of these pathogens employ a defense strategy that...
2.
Patel D, Stogios P, Jaroszewski L, Urbanus M, Sedova M, Semper C, et al.
Mol Syst Biol
. 2024 Nov;
21(1):59-89.
PMID: 39562741
Legionella pneumophila utilizes the Dot/Icm type IVB secretion system to deliver hundreds of effector proteins inside eukaryotic cells to ensure intracellular replication. Our understanding of the molecular functions of the...
3.
Semper C, Watanabe N, Karimullina E, Patel D, Di Leo R, Castellanos M, et al.
Nucleic Acids Res
. 2024 Jul;
52(14):8431-8442.
PMID: 38979576
Borrelia spirochetes are the causative agents of Lyme disease and relapsing fever, two of the most common tick-borne illnesses. A characteristic feature of these spirochetes is their highly segmented genomes...
4.
Syriste L, Patel D, Stogios P, Skarina T, Patel D, Savchenko A
mBio
. 2024 Feb;
15(3):e0322123.
PMID: 38335095
The survival of spp. as intracellular pathogens relies on the combined action of protein effectors delivered inside their eukaryotic hosts by the Dot/Icm (efective in rganelle rafficking/ntraellular ultiplication) type IVb...
5.
Penner T, Lorente Cobo N, Patel D, Patel D, Savchenko A, Brassinga A, et al.
Protein Sci
. 2023 Dec;
33(3):e4889.
PMID: 38160319
Legionella are freshwater Gram-negative bacteria that in their normal environment infect protozoa. However, this adaptation also allows Legionella to infect human alveolar macrophages and cause pneumonia. Central to Legionella pathogenesis...