Deepak Srivastava
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Explore the profile of Deepak Srivastava including associated specialties, affiliations and a list of published articles.
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201
Citations
17582
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Recent Articles
11.
Krup A, Winchester S, Ranade S, Agrawal A, Devine W, Sinha T, et al.
Development
. 2023 Mar;
150(9).
PMID: 36994838
Transcriptional networks governing cardiac precursor cell (CPC) specification are incompletely understood owing, in part, to limitations in distinguishing CPCs from non-cardiac mesoderm in early gastrulation. We leveraged detection of early...
12.
Alexanian M, Padmanabhan A, Nishino T, Travers J, Ye L, Lee C, et al.
bioRxiv
. 2023 Jan;
PMID: 36711864
Chronic inflammation and tissue fibrosis are common stress responses that worsen organ function, yet the molecular mechanisms governing their crosstalk are poorly understood. In diseased organs, stress-induced changes in gene...
13.
Bock-Marquette I, Maar K, Maar S, Lippai B, Faskerti G, Gallyas Jr F, et al.
Int Immunopharmacol
. 2023 Jan;
116:109741.
PMID: 36709593
Our dream of defeating the processes of organ damage and aging remains a challenge scientists pursued for hundreds of years. Although the goal is to successfully treat the body as...
14.
Smith G, Padmanabhan A, Lau B, Pampana A, Li L, Lee C, et al.
Sci Transl Med
. 2022 Sep;
14(662):eabj8670.
PMID: 36103516
The low-density lipoprotein receptor (LDLR) controls cellular delivery of cholesterol and clears LDL from the bloodstream, protecting against atherosclerotic heart disease, the leading cause of death in the United States....
15.
Zhu L, Choudhary K, Gonzalez-Teran B, Ang Y, Thomas R, Stone N, et al.
Circulation
. 2022 Aug;
146(10):770-787.
PMID: 35938400
Background: GATA4 (GATA-binding protein 4), a zinc finger-containing, DNA-binding transcription factor, is essential for normal cardiac development and homeostasis in mice and humans, and mutations in this gene have been...
16.
Srivastava D
Science
. 2022 Jun;
376(6599):1271-1272.
PMID: 35709257
The cytokine meteorin-like (METRNL) improves cardiac function after heart attack in mice.
17.
Little M, Morrison S, Rossant J, Srivastava D, Daley G
Cell Stem Cell
. 2022 Jun;
29(6):876-878.
PMID: 35659873
This year, Cell Stem Cell and the International Society for Stem Cell Research (ISSCR) are celebrating their 15 and 20 anniversaries, respectively. We took the opportunity to ask the current...
18.
Willcox J, Geiger J, Morton S, McKean D, Quiat D, Gorham J, et al.
Am J Hum Genet
. 2022 Apr;
109(5):961-966.
PMID: 35397206
The well-established manifestation of mitochondrial mutations in functional cardiac disease (e.g., mitochondrial cardiomyopathy) prompted the hypothesis that mitochondrial DNA (mtDNA) sequence and/or copy number (mtDNAcn) variation contribute to cardiac defects...
19.
Gonzalez-Teran B, Pittman M, Felix F, Thomas R, Richmond-Buccola D, Huttenhain R, et al.
Cell
. 2022 Feb;
185(5):794-814.e30.
PMID: 35182466
Congenital heart disease (CHD) is present in 1% of live births, yet identification of causal mutations remains challenging. We hypothesized that genetic determinants for CHDs may lie in the protein...
20.
Abouleisa R, Salama A, Ou Q, Tang X, Solanki M, Guo Y, et al.
Circulation
. 2022 Jan;
145(17):1339-1355.
PMID: 35061545
Background: The regenerative capacity of the heart after myocardial infarction is limited. Our previous study showed that ectopic introduction of 4 cell cycle factors (4F; CDK1 [cyclin-dependent kinase 1], CDK4...