Deepa Chand
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Explore the profile of Deepa Chand including associated specialties, affiliations and a list of published articles.
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21
Citations
762
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Recent Articles
1.
Sun R, Bustamante M, Gurusamy V, Lebwohl M, Gottlieb A, Mease P, et al.
Dermatol Ther (Heidelb)
. 2024 Mar;
14(3):729-743.
PMID: 38451423
Introduction: Secukinumab is an anti-interleukin (IL)-17A monoclonal antibody indicated for multiple immunological disorders. Here, we aim to summarize secukinumab safety in clinical trials (CTs) and post-marketing setting (PMS) until 25 ...
2.
Hudry E, Aihara F, Meseck E, Mansfield K, McElroy C, Chand D, et al.
Mol Ther
. 2023 Jul;
31(10):2999-3014.
PMID: 37515322
Hepatotoxicity associated with intravenous/intrathecal adeno-associated virus (AAV) gene therapy has been observed in preclinical species and patients. In nonhuman primates, hepatotoxicity following self-complementary AAV9 administration varies from asymptomatic transaminase elevation...
3.
Tukov F, Mansfield K, Milton M, Meseck E, Penraat K, Chand D, et al.
Hum Gene Ther
. 2022 Mar;
33(13-14):740-756.
PMID: 35331006
Intravenous onasemnogene abeparvovec is approved for the treatment of spinal muscular atrophy in children < 2 years. For later-onset patients, intrathecal onasemnogene abeparvovec may be advantageous over intravenous administration. Recently,...
4.
Mercuri E, Muntoni F, Baranello G, Masson R, Boespflug-Tanguy O, Bruno C, et al.
Lancet Neurol
. 2021 Sep;
20(10):832-841.
PMID: 34536405
Background: Spinal muscular atrophy is a rare, autosomal recessive, neuromuscular disease caused by biallelic loss of the survival motor neuron 1 (SMN1) gene, resulting in motor neuron dysfunction. In this...
5.
Chand D, Mohr F, McMillan H, Tukov F, Montgomery K, Kleyn A, et al.
J Hepatol
. 2020 Nov;
74(3):560-566.
PMID: 33186633
Background & Aims: Spinal muscular atrophy (SMA) is an autosomal recessive, childhood-onset motor neuron disease. Onasemnogene abeparvovec (OA) is a gene therapy designed to address SMA's root cause. In pivotal...
6.
Xiao N, Stolfi A, Malatesta-Muncher R, Bholah R, Kogon A, Eddington A, et al.
Int J Nephrol
. 2019 Dec;
2019:7828406.
PMID: 31885919
Introduction: There is a paucity of information about risk behaviors in adolescents with chronic kidney disease (CKD). We designed this study to assess the prevalence of risk behaviors among teens...
7.
Raina R, Grewal M, Blackford M, Symons J, Somers M, Licht C, et al.
Pediatr Nephrol
. 2019 Aug;
34(11):2427-2448.
PMID: 31446483
Background: Intentional or unintentional ingestions among children and adolescents are common. There are a number of ingestions amenable to renal replacement therapy (RRT). Methods: We systematically searched PubMed/Medline, Embase, and...
8.
Raina R, Lam S, Raheja H, Krishnappa V, Hothi D, Davenport A, et al.
Pediatr Nephrol
. 2019 Feb;
34(5):925-941.
PMID: 30734850
Intradialytic hypotension (IDH) is a common adverse event resulting in premature interruption of hemodialysis, and consequently, inadequate fluid and solute removal. IDH occurs in response to the reduction in blood...
9.
Raina R, Vijayaraghavan P, Kapur G, Sethi S, Krishnappa V, Kumar D, et al.
Semin Dial
. 2017 Nov;
31(3):289-299.
PMID: 29105839
Hemodialysis (HD) in neonates and infants poses unique challenges due to high risks of mortality attributable to obligatory small blood flow volumes. Although HD is often necessary in neonates, its...
10.
Gbadegesin R, Adeyemo A, Webb N, Greenbaum L, Abeyagunawardena A, Thalgahagoda S, et al.
J Am Soc Nephrol
. 2014 Oct;
26(7):1701-10.
PMID: 25349203
Steroid-sensitive nephrotic syndrome (SSNS) accounts for >80% of cases of nephrotic syndrome in childhood. However, the etiology and pathogenesis of SSNS remain obscure. Hypothesizing that coding variation may underlie SSNS...