Debra A MacKenzie
Overview
Explore the profile of Debra A MacKenzie including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
227
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0
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Recent Articles
1.
McCormack L, MacKenzie D, Deutsch A, Beene D, Hockett C, Ziegler K, et al.
J Rural Health
. 2024 Dec;
41(1):e12908.
PMID: 39731317
Purpose: The Environmental influences on Child Health Outcomes (ECHO) Cohort has enrolled over 60,000 children to examine how early environmental factors (broadly defined) are associated with key child health outcomes....
2.
Schilz J, Dashner-Titus E, Simmons K, Erdei E, Bolt A, MacKenzie D, et al.
Toxicol Appl Pharmacol
. 2022 Sep;
454:116252.
PMID: 36152676
Uranium is a naturally occurring element found in the environment as a mixture of isotopes with differing radioactive properties. Enrichment of mined material results in depleted uranium waste with substantially...
3.
Schilz J, Dashner-Titus E, Luo L, Simmons K, MacKenzie D, Hudson L
Toxicol Rep
. 2021 Dec;
8:1917-1929.
PMID: 34926170
Communities in the western region of the United States experience environmental exposure to metal mixtures from living in proximity to numerous unremediated abandoned uranium mines. Metals including arsenic and uranium...
4.
Price D, McBride A, Anton M, Kusewitt D, Norenberg J, MacKenzie D, et al.
PLoS One
. 2016 Dec;
11(12):e0169107.
PMID: 28036366
Lung cancer has the highest mortality rate of any tissue-specific cancer in both men and women. Research continues to investigate novel drugs and therapies to mitigate poor treatment efficacy, but...
5.
Fajardo A, MacKenzie D, Olguin S, Scariano J, Rabinowitz I, Thompson T
PLoS One
. 2016 Mar;
11(3):e0151525.
PMID: 26986969
Tocopherylquinone (TQ), the oxidation product of alpha-tocopherol (AT), is a bioactive molecule with distinct properties from AT. In this study, AT and TQ are investigated for their comparative effects on...
6.
Oprea T, Bauman J, Bologa C, Buranda T, Chigaev A, Edwards B, et al.
Drug Discov Today Ther Strateg
. 2012 Feb;
8(3-4):61-69.
PMID: 22368688
Academia and small business research units are poised to play an increasing role in drug discovery, with drug repurposing as one of the major areas of activity. Here we summarize...
7.
Fajardo A, MacKenzie D, Ji M, Deck L, Vander Jagt D, Thompson T, et al.
Prostate
. 2011 Jul;
72(6):612-25.
PMID: 21796654
Background: The androgen receptor (AR) plays a critical role in prostate cancer development and progression. Therefore, the inhibition of AR function is an established therapeutic intervention. Since the expression of...
8.
MacKenzie D, Seroogy C
Acta Haematol
. 2009 Nov;
122(4):230-7.
PMID: 19887782
Background/aims: Despite a sophisticated understanding of the hematopoietic developmental program at the transcriptional level, our understanding of the role of E3 ubiquitin ligases remains underdeveloped. The E3 ubiquitin ligase, GRAIL...
9.
Dennis M, Bowles H, MacKenzie D, Burchiel S, Edwards B, Sklar L, et al.
Cytometry A
. 2008 Mar;
73(5):390-9.
PMID: 18340645
The androgen receptor (AR) is a steroid hormone receptor which regulates transcription of androgen-sensitive genes and is responsible for the development and maintenance of male secondary sexual characteristics. Chemicals that...
10.
Newkirk K, MacKenzie D, Bakaletz A, Hudson L, Kusewitt D
J Invest Dermatol
. 2007 Jul;
128(2):361-9.
PMID: 17637818
Slug (Snail2) is a member of the Snail family of zinc-finger transcription factors with regulatory functions in development, tissue morphogenesis, and tumor progression. Little is known about Slug in normal...