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» Authors » Debora B Mello

Debora B Mello

Explore the profile of Debora B Mello including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 7
Citations 54
Followers 0
Related Specialties
Biochemistry
Molecular Biology
Chemistry
Top 10 Co-Authors
Antonio C Campos de Carvalho
Adriana B Carvalho
Guilherme V Brasil
Humberto Muzi-Filho
Thuany Crisostomo
Rafael Luzes
Isalira P Ramos
Adalberto Vieyra
Nazareth N Rocha
Regina Coeli Dos Santos Goldenberg
Published In
Int J Mol Sci
Basic Res Cardiol
Front Cell Infect Microbiol
Stem Cell Res Ther
Metabol Open
Affiliations
Soon will be listed here.
Recent Articles
1.
Male Wistar Rats Chronically Fed with a High-Fat Diet Develop Inflammatory and Ionic Transport Angiotensin-(3-4)-Sensitive Myocardial Lesions but Preserve Echocardiographic Parameters
Crisostomo T, Luzes R, Goncalves M, Pardal M, Muzi-Filho H, Costa-Sarmento G, et al.
Int J Mol Sci . 2024 Nov; 25(22). PMID: 39596537
The central aim of this study was to investigate whether male Wistar rats chronically fed a high-fat diet (HFD) over 106 days present high levels of interleukin-6 (IL-6) and tumor...
2.
Mesenchymal Stromal Cell-Based Products: Challenges and Clinical Therapeutic Options
Mello D, Mesquita F, Silva Dos Santos D, Asensi K, Dias M, Campos de Carvalho A, et al.
Int J Mol Sci . 2024 Jun; 25(11). PMID: 38892249
Mesenchymal stromal cell (MSC)-based advanced therapy medicinal products (ATMPs) are being tried in a vast range of clinical applications. These cells can be isolated from different donor tissues by using...
3.
Liver steatosis, cardiac and renal fibrosis, and hypertension in overweight rats: Angiotensin-(3-4)-sensitive hepatocardiorenal syndrome
Crisostomo T, Pardal M, Herdy S, Muzi-Filho H, Mello D, Takiya C, et al.
Metabol Open . 2022 Apr; 14:100176. PMID: 35392380
Overweight/obesity is a growing pandemic that affects many organs and tissues. We have investigated whether a high-lipid diet provokes an imbalance between type 1 and type 2 angiotensin II (Ang...
4.
Echocardiographic Measurements in a Preclinical Model of Chronic Chagasic Cardiomyopathy in Dogs: Validation and Reproducibility
Carvalho E, Ramos I, Nascimento A, Brasil G, Mello D, Oti M, et al.
Front Cell Infect Microbiol . 2019 Oct; 9:332. PMID: 31616643
The failure to translate preclinical results to the clinical setting is the rule, not the exception. One reason that is frequently overlooked is whether the animal model reproduces distinctive features...
5.
Adipose Tissue-Derived Mesenchymal Stromal Cells Protect Mice Infected with Trypanosoma cruzi from Cardiac Damage through Modulation of Anti-parasite Immunity
Mello D, Ramos I, Mesquita F, Brasil G, Rocha N, Takiya C, et al.
PLoS Negl Trop Dis . 2015 Aug; 9(8):e0003945. PMID: 26248209
Background: Chagas disease, caused by the protozoan Trypanosoma cruzi (T. cruzi), is a complex disease endemic in Central and South America. It has been gathering interest due to increases in...
6.
Improvement of cardiac function by placenta-derived mesenchymal stem cells does not require permanent engraftment and is independent of the insulin signaling pathway
Passipieri J, Kasai-Brunswick T, Suhett G, Martins A, Brasil G, Campos D, et al.
Stem Cell Res Ther . 2014 Aug; 5(4):102. PMID: 25145631
Introduction: The objective of this work was to evaluate the efficacy of placenta-derived mesenchymal stem cell (MSC) therapy in a mouse model of myocardial infarction (MI). Since MSCs can be...
7.
G-CSF does not improve systolic function in a rat model of acute myocardial infarction
Werneck-de-Castro J, Costa-E-Sousa R, de Oliveira P, Pinho-Ribeiro V, Mello D, Pecanha R, et al.
Basic Res Cardiol . 2006 Jun; 101(6):494-501. PMID: 16783485
Objective: Granulocyte colony-stimulating factor (G-CSF) has been reported to improve cardiac performance by increasing the number of bone marrow stem cell in the peripheral circulation. The aim of this study...