Humberto Muzi-Filho
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Explore the profile of Humberto Muzi-Filho including associated specialties, affiliations and a list of published articles.
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21
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114
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Recent Articles
1.
Moreno-Loaiza O, Soares V, de Assumpcao Souza M, Vera-Nunez N, Rodriguez de Yurre Guirao A, da Silva T, et al.
Nat Cardiovasc Res
. 2025 Feb;
PMID: 39915330
Atrial fibrillation (AF) is more prevalent in patients with elevated interleukin (IL)-1β levels. Here we show that daily administration of IL-1β for 15 days sensitizes mice to AF, leading to...
2.
Crisostomo T, Luzes R, Goncalves M, Pardal M, Muzi-Filho H, Costa-Sarmento G, et al.
Int J Mol Sci
. 2024 Nov;
25(22).
PMID: 39596537
The central aim of this study was to investigate whether male Wistar rats chronically fed a high-fat diet (HFD) over 106 days present high levels of interleukin-6 (IL-6) and tumor...
3.
Nossar L, Lopes J, Pereira-Acacio A, Costa-Sarmento G, Rachid R, Wendt C, et al.
Biochem Biophys Res Commun
. 2024 Aug;
739:150583.
PMID: 39182354
This study investigated whether chronic undernutrition alters the mitochondrial structure and function in renal proximal tubule cells, thus impairing fluid transport and homeostasis. We previously showed that chronic undernutrition downregulates...
4.
Cirilo M, Santos V, Lima N, Muzi-Filho H, Paixao A, Vieyra A, et al.
An Acad Bras Cienc
. 2024 Apr;
96(1):e20230971.
PMID: 38597493
Paraquat (1,1'-dimethyl-4,4'-bipyridyl dichloride) is an herbicide widely used worldwide and officially banned in Brazil in 2020. Kidney lesions frequently occur, leading to acute kidney injury (AKI) due to exacerbated reactive...
5.
Pereira-Acacio A, Veloso-Santos J, Alves-Bezerra D, Costa-Sarmento G, Muzi-Filho H, Vieyra A
Physiol Rep
. 2023 Sep;
11(17):e15820.
PMID: 37667414
Hypertension is a pandemic nowadays. We aimed to investigate whether chronic undernutrition modifies the response to the antihypertensive drug rostafuroxin in juvenile hypertensive rats. Chronic undernutrition was induced in male...
6.
Pereira-Acacio A, Veloso-Santos J, Nossar L, Costa-Sarmento G, Muzi-Filho H, Vieyra A
PLoS One
. 2022 Aug;
17(8):e0273385.
PMID: 35984814
We investigated the mechanisms by which chronic administration of a multideficient diet after weaning alters bodily Na+ handling, and culminates in high systolic blood pressure (SBP) at a juvenile age....
7.
Crisostomo T, Pardal M, Herdy S, Muzi-Filho H, Mello D, Takiya C, et al.
Metabol Open
. 2022 Apr;
14:100176.
PMID: 35392380
Overweight/obesity is a growing pandemic that affects many organs and tissues. We have investigated whether a high-lipid diet provokes an imbalance between type 1 and type 2 angiotensin II (Ang...
8.
Jannuzzi L, Pereira-Acacio A, Ferreira B, Silva-Pereira D, Veloso-Santos J, Alves-Bezerra D, et al.
Nutr Neurosci
. 2021 Apr;
25(9):1973-1994.
PMID: 33871318
Undernutrition is characterized by an imbalance of essential nutrients with an insufficient nutritional intake, a disorder in which the clinical manifestations in most cases are the result of the economic...
9.
Lima N, Farias W, Cirilo M, Oliveira A, Farias J, Aires R, et al.
Life Sci
. 2020 Dec;
266:118879.
PMID: 33310030
Acute renal injury (AKI) is a risk factor for the development of hypertension, which involves oxidative stress, changes in Na handling, and the intrarenal renin-angiotensin-aldosterone system (RAAS) as underlying mechanisms....
10.
Muzi-Filho H, Jannuzzi L, Bouzan A, Alves-Barros S, Alves-Bezerra D, Pereira-Acacio A, et al.
Cell Physiol Biochem
. 2020 Nov;
54(6):1143-1162.
PMID: 33201644
Background/aims: Chronic malnutrition (M) affects >1 billion people worldwide. Epidemiological data point to long-term renal and cardiovascular outcomes (e.g. arterial hypertension, cardiorenal syndromes). The renin-angiotensin-aldosterone system (RAAS) has been implicated...