Debashree Mukherjea
Overview
Explore the profile of Debashree Mukherjea including associated specialties, affiliations and a list of published articles.
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37
Citations
1687
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Recent Articles
1.
Ramkumar V, Mukherjea D, Dhukhwa A, Rybak L
Antioxidants (Basel)
. 2021 Dec;
10(12).
PMID: 34943021
Hearing loss is a significant health problem that can result from a variety of exogenous insults that generate oxidative stress and inflammation. This can produce cellular damage and impairment of...
2.
Ramkumar V, Sheth S, Dhukhwa A, Al Aameri R, Rybak L, Mukherjea D
Antioxid Redox Signal
. 2021 Sep;
36(16-18):1158-1170.
PMID: 34465184
Transient receptor potential (TRP) channels are cation-gated channels that serve as detectors of various sensory modalities, such as pain, heat, cold, and taste. These channels are expressed in the inner...
3.
Broderick M, Prince A, Dhukhwa A, Mukherjea D, Jiang P, Campbell K, et al.
Otol Neurotol
. 2021 May;
42(8):1261-1268.
PMID: 34049329
Hypothesis: Moringa extract, a naturally occurring anti-oxidant, protects against aminoglycoside-induced hair cell death and hearing loss within the organ of Corti. Background: Reactive oxygen species (ROS) arise primarily in the...
4.
Dhukhwa A, Al Aameri R, Sheth S, Mukherjea D, Rybak L, Ramkumar V
Sci Rep
. 2021 Apr;
11(1):8116.
PMID: 33854102
Regulators of G protein signaling (RGS) accelerate the GTPase activity of G proteins to enable rapid termination of the signals triggered by G protein-coupled receptors (GPCRs). Activation of several GPCRs,...
5.
Rybak L, Ramkumar V, Mukherjea D
Front Neurol
. 2021 Mar;
12:652674.
PMID: 33767665
It is well-known that aminoglycoside antibiotics can cause significant hearing loss and vestibular deficits that have been described in animal studies and in clinical reports. The purpose of this review...
6.
Mukherjea D, Dhukhwa A, Sapra A, Bhandari P, Woolford K, Franke J, et al.
Expert Opin Drug Metab Toxicol
. 2020 Aug;
16(10):965-982.
PMID: 32757852
Introduction: Cisplatin is a highly effective chemotherapeutic agent against a variety of solid tumors in adults and in children. Unfortunately, a large percentage of patients suffer permanent sensorineural hearing loss....
7.
Targeting Inflammatory Processes Mediated by TRPVI and TNF-α for Treating Noise-Induced Hearing Loss
Dhukhwa A, Bhatta P, Sheth S, Korrapati K, Tieu C, Mamillapalli C, et al.
Front Cell Neurosci
. 2019 Oct;
13:444.
PMID: 31632242
Noise trauma is the most common cause of hearing loss in adults. There are no known FDA approved drugs for prevention or rescue of noise-induced hearing loss (NIHL). In this...
8.
Rybak L, Dhukhwa A, Mukherjea D, Ramkumar V
Front Cell Neurosci
. 2019 Jul;
13:300.
PMID: 31338024
Systemic delivery of therapeutics for targeting the cochlea to prevent or treat hearing loss is challenging. Systemic drugs have to cross the blood-labyrinth barrier (BLB). BLB can significantly prevent effective...
9.
Sheth S, Sheehan K, Dhukhwa A, Al Aameri R, Mamillapalli C, Mukherjea D, et al.
Sci Rep
. 2019 Jul;
9(1):9571.
PMID: 31267026
Adenosine A receptors (AAR) are well characterized for their role in cytoprotection. Previous studies have demonstrated the presence of these receptors in the cochlea where their activation were shown to...
10.
Rybak L, Mukherjea D, Ramkumar V
Semin Hear
. 2019 May;
40(2):197-204.
PMID: 31036996
Cisplatin is a highly effective antineoplastic agent used to treat solid tumors. Unfortunately, the administration of this drug leads to significant side effects, including ototoxicity, nephrotoxicity, and neurotoxicity. This review...