Dean E Brenner
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Explore the profile of Dean E Brenner including associated specialties, affiliations and a list of published articles.
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100
Citations
4340
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Recent Articles
1.
Jiang C, Niu Z, Green M, Zhao L, Raupp S, Pannecouk B, et al.
J Immunother Cancer
. 2021 Jul;
9(7).
PMID: 34321277
Immunotherapy for cancer is now a standard pillar in the armamentarium of treatments for many cancers. Immune checkpoint inhibitors, in particular, have resulted in significant therapeutic benefit and prolongation of...
2.
Shen Y, Sen A, Turgeon D, Ren J, Graifman G, Ruffin 4th M, et al.
Nutr Cancer
. 2021 Mar;
74(2):565-578.
PMID: 33757398
This study evaluated changes in fatty acids from sera, red blood cells, and colonic biopsies from a phase Ib clinical trial of personalized ω-3 fatty acid dosing in 47 healthy...
3.
Sen A, Zhao L, Djuric Z, Turgeon D, Ruffin M, Smith W, et al.
Am J Prev Med
. 2020 Sep;
59(4):e167-e173.
PMID: 32951684
Introduction: In biomarker-driven clinical trials, translational strategies typically involve moving findings from animal experiments to human trials. Typically, the translation is static, using a fixed model derived from animal experiments...
4.
Colacino J, Djuric Z, Brenner D
Cancer Prev Res (Phila)
. 2020 Aug;
13(10):803-806.
PMID: 32839206
Obesity is the second leading environmental association with cancer risk; yet, the mechanisms by which obesity drives carcinogenesis are poorly understood. The paper published in this issue of Cancer Prevention...
5.
Hill E, Esper R, Sen A, Simon B, Aslam M, Jiang Y, et al.
J Nutr Biochem
. 2019 Jul;
71:45-53.
PMID: 31272031
Chronic low-grade adipose inflammation, characterized by aberrant adipokine production and pro-inflammatory macrophage activation/polarization is associated with increased risk of breast cancer. Adipocyte fatty acid composition is influenced by dietary availability...
6.
Djuric Z, Bassis C, Plegue M, Sen A, Turgeon D, Herman K, et al.
J Nutr
. 2019 May;
149(7):1170-1179.
PMID: 31051496
Background: The intestinal microbiome is an important determinant of inflammatory balance in the colon that may affect response to dietary agents. Objective: This is a secondary analysis of a clinical...
7.
Wilson M, Sen A, Bridges D, Turgeon D, Brenner D, Smith W, et al.
Prostaglandins Leukot Essent Fatty Acids
. 2018 Nov;
139:14-19.
PMID: 30471768
This study evaluated whether mRNA expression of major genes regulating formation of prostaglandin (PG)E in the colon and colonic fatty acid concentrations are associated with the reduction in colonic mucosal...
8.
Cooper G, Markowitz S, Chen Z, Tuck M, Willis J, Berger B, et al.
Cancer
. 2018 Sep;
124(19):3876-3880.
PMID: 30193399
Background: Multitarget stool DNA (mt-sDNA) is an approved method for colon cancer screening that is especially relevant for patients who cannot undergo colonoscopy. Although the test performance has been evaluated...
9.
Cooper G, Markowitz S, Chen Z, Tuck M, Willis J, Berger B, et al.
Dig Dis Sci
. 2018 Mar;
63(6):1449-1453.
PMID: 29516325
Background: There is uncertainty as to the appropriate follow-up of patients who test positive on multimarker stool DNA (sDNA) testing and have a colonoscopy without neoplasia. Aims: To determine the...
10.
Dame M, Attili D, McClintock S, Dedhia P, Ouillette P, Hardt O, et al.
Development
. 2018 Feb;
145(6).
PMID: 29467240
The intestine is maintained by stem cells located at the base of crypts and distinguished by the expression of LGR5. Genetically engineered mouse models have provided a wealth of information...