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Dean Brenner

Explore the profile of Dean Brenner including associated specialties, affiliations and a list of published articles. Areas
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Articles 14
Citations 1835
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Recent Articles
1.
Furuya H, Brenner D, Rosser C
J Transl Med . 2017 May; 15(1):88. PMID: 28460639
Over the past decade, we have seen an unparalleled growth in our knowledge of cancer biology and the translation of this biology into a new generation of therapeutic tools that...
2.
Xue X, Ramakrishnan S, Weisz K, Triner D, Xie L, Attili D, et al.
Cell Metab . 2016 Aug; 24(3):447-461. PMID: 27546461
Dietary iron intake and systemic iron balance are implicated in colorectal cancer (CRC) development, but the means by which iron contributes to CRC are unclear. Gene expression and functional studies...
3.
Yu M, Carter K, Makar K, Vickers K, Ulrich C, Schoen R, et al.
Epigenetics . 2015 Jul; 10(9):803-9. PMID: 26186366
Aberrant DNA methylation is a common epigenetic alteration found in colorectal adenomas and cancers and plays a role in cancer initiation and progression. Aberrantly methylated DNA loci can also be...
4.
Nadal E, Chen G, Prensner J, Shiratsuchi H, Sam C, Zhao L, et al.
J Thorac Oncol . 2014 Aug; 9(10):1513-22. PMID: 25170638
Introduction: The aim of this study was to examine the effects of KRAS mutant subtypes on the outcome of patients with resected lung adenocarcinoma (AC). Methods: Using clinical and sequencing...
5.
Kostic A, Chun E, Robertson L, Glickman J, Gallini C, Michaud M, et al.
Cell Host Microbe . 2013 Aug; 14(2):207-15. PMID: 23954159
Increasing evidence links the gut microbiota with colorectal cancer. Metagenomic analyses indicate that symbiotic Fusobacterium spp. are associated with human colorectal carcinoma, but whether this is an indirect or causal...
6.
Azrad M, Zhang K, Vollmer R, Madden J, Polascik T, Snyder D, et al.
PLoS One . 2013 Jan; 7(12):e53104. PMID: 23285256
Previous observational studies have reported associations between prostate cancer and alpha-linolenic acid (ALA). However, few investigations have been able to study this relationship prospectively and in well-controlled settings. Moreover, no...
7.
Normolle D, Ruffin M, Brenner D
Cancer Inform . 2009 Mar; 1:25-31. PMID: 19305629
The design of early-phase studies of putative screening markers in clinical populations is discussed. Biological, epidemiological, statistical and computational issues all affect the design of early-phase studies of these markers,...
8.
Wang L, Correa C, Hayman J, Zhao L, Cease K, Brenner D, et al.
Int J Radiat Oncol Biol Phys . 2009 Feb; 74(3):790-5. PMID: 19231108
Purpose: To determine whether time to treatment (TTT) has an effect on overall survival (OS) in patients with unresectable or medically inoperable Stage III non-small cell lung cancer (NSCLC) and...
9.
Zhao L, Wang L, Ji W, Wang X, Zhu X, Hayman J, et al.
Int J Radiat Oncol Biol Phys . 2009 Feb; 74(5):1385-90. PMID: 19231104
Purpose: To test whether radiation-induced elevations of transforming growth factor-beta1 (TGF-beta1) during radiation therapy (RT) correlate with radiation-induced lung toxicity (RILT) in patients with non-small-cell lung cancer (NSCLC) and to...
10.
Demark-Wahnefried W, Polascik T, George S, Switzer B, Madden J, Ruffin 4th M, et al.
Cancer Epidemiol Biomarkers Prev . 2008 Dec; 17(12):3577-87. PMID: 19064574
Background: Prostate cancer affects one of six men during their lifetime. Dietary factors are postulated to influence the development and progression of prostate cancer. Low-fat diets and flaxseed supplementation may...