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Dawn Waterworth

Explore the profile of Dawn Waterworth including associated specialties, affiliations and a list of published articles. Areas
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Articles 54
Citations 7772
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Recent Articles
1.
Kurki M, Karjalainen J, Palta P, Sipila T, Kristiansson K, Donner K, et al.
Nature . 2023 Feb; 615(7952):E19. PMID: 36829046
No abstract available.
2.
Kurki M, Karjalainen J, Palta P, Sipila T, Kristiansson K, Donner K, et al.
Nature . 2023 Jan; 613(7944):508-518. PMID: 36653562
Population isolates such as those in Finland benefit genetic research because deleterious alleles are often concentrated on a small number of low-frequency variants (0.1% ≤ minor allele frequency < 5%)....
3.
Siddiqui M, Smith G, St Jean P, Dawed A, Bell S, Soto-Pedre E, et al.
Diabetologia . 2021 Sep; 65(1):101-112. PMID: 34562103
Aims/hypothesis: Lipoprotein-associated phospholipase A2 (Lp-PLA2) activity has an independent prognostic association with major coronary events (MCE). However, no study has investigated whether type 2 diabetes status modifies the effect of...
4.
Schunk S, Kleber M, Marz W, Pang S, Zewinger S, Triem S, et al.
Eur Heart J . 2021 Mar; 42(18):1742-1756. PMID: 33748830
Aims: Inflammation plays an important role in cardiovascular disease (CVD) development. The NOD-like receptor protein-3 (NLRP3) inflammasome contributes to the development of atherosclerosis in animal models. Components of the NLRP3...
5.
Cuellar-Partida G, Tung J, Eriksson N, Albrecht E, Aliev F, Andreassen O, et al.
Nat Hum Behav . 2020 Sep; 5(1):59-70. PMID: 32989287
Handedness has been extensively studied because of its relationship with language and the over-representation of left-handers in some neurodevelopmental disorders. Using data from the UK Biobank, 23andMe and the International...
6.
Zheng J, Haberland V, Baird D, Walker V, Haycock P, Hurle M, et al.
Nat Genet . 2020 Sep; 52(10):1122-1131. PMID: 32895551
The human proteome is a major source of therapeutic targets. Recent genetic association analyses of the plasma proteome enable systematic evaluation of the causal consequences of variation in plasma protein...
7.
Shah S, Henry A, Roselli C, Lin H, Sveinbjornsson G, Fatemifar G, et al.
Nat Commun . 2020 Jan; 11(1):163. PMID: 31919418
Heart failure (HF) is a leading cause of morbidity and mortality worldwide. A small proportion of HF cases are attributable to monogenic cardiomyopathies and existing genome-wide association studies (GWAS) have...
8.
Mokry L, Zhou S, Guo C, Scott R, Devey L, Langenberg C, et al.
Sci Rep . 2019 Jun; 9(1):9386. PMID: 31253830
Support from human genetics increases the probability of success in drug development. However, few examples exist of successful genomically-driven drug repositioning. Given that a Mendelian form of severe enterocolitis is...
9.
James G, Reisberg S, Lepik K, Galwey N, Avillach P, Kolberg L, et al.
PLoS One . 2019 Apr; 14(4):e0215026. PMID: 30978214
The Estonian Biobank, governed by the Institute of Genomics at the University of Tartu (Biobank), has stored genetic material/DNA and continuously collected data since 2002 on a total of 52,274...
10.
Stewart R, Held C, Krug-Gourley S, Waterworth D, Stebbins A, Chiswell K, et al.
J Am Heart Assoc . 2019 Mar; 8(7):e010641. PMID: 30897999
Background Vascular risk factors have been associated with differences in cognitive performance in epidemiological studies, but evidence in patients with coronary heart disease is more limited. Methods and Results The...